TFII-I Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NB100-61053

Novus Biologicals, part of Bio-Techne
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NB100-61053
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Key Product Details

Validated by

Independent Antibodies

Species Reactivity

Human, Mouse

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Immunoprecipitation, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

0.2 mg/ml

View all TFII-I Antibodies »

Product Specifications

Immunogen

The immunogen recognized by this antibody maps to a region between residue 935 and 985 of human general transcription factor II, i using the numbering given in entry NP_127492.1 (GeneID 2969).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for TFII-I Antibody

Western Blot: TFII-I Antibody [NB100-61053]

Western Blot: TFII-I Antibody [NB100-61053]

Western Blot: TFII-I Antibody [NB100-61053] - Detection of Human GTF2I/TFII-I on HeLa whole cell lysate. GTF2I/TFII-I was also immunoprecipitated by rabbit anti-GTF2I/TFII-I antibody NB100-61054.
Immunohistochemistry: TFII-I Antibody [NB100-61053]

Immunohistochemistry: TFII-I Antibody [NB100-61053]

Immunohistochemistry: TFII-I Antibody [NB100-61053] - Sample: FFPE section of human breast carcinoma (left) and mouse teratoma (right). Antibody: Affinity purified rabbit anti-GTF2I/TFII-I used at a dilution of 1:200 (1ug/ml). Detection: DAB

Applications for TFII-I Antibody

Application
Recommended Usage

Immunohistochemistry

1:10-1:500

Immunohistochemistry-Paraffin

1:10-1:500

Immunoprecipitation

2-5 ug/mg lysate

Western Blot

1:2000-1:10000
Application Notes
Epitope retrieval with citrate buffer pH6.0 is recommended for FFPE tissue sections.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

TBS and 0.1% BSA

Preservative

0.09% Sodium Azide

Concentration

0.2 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: TFII-I

This gene encodes a multifunctional phosphoprotein with roles in transcription and signal transduction. It is deleted in Williams-Beuren syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at chromosome 7q11.23. The exon(s) encoding 5' UTR has not been fully defined, but this gene is known to contain at least 34 exons, and its alternative splicing generates 4 transcript variants.

Alternate Names

BAP-135,135kD, BAP135WBS, Bruton tyrosine kinase-associated protein 135, BTKAP1, DIWS, FLJ38776, FLJ56355, general transcription factor II, i, general transcription factor IIi, general transcription factor II-I, GTFII-I, IB291, SPINBTK-associated protein 135, TFII-ISRF-Phox1-interacting protein, WBSCR6, Williams-Beuren syndrome chromosome region 6

Entrez Gene IDs

2969 (Human)

Gene Symbol

GTF2I

UniProt

P78347 (Human)

Additional TFII-I Products

Product Documents for TFII-I Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for TFII-I Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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