Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Immunoprecipitation

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

1.0 mg/ml

View all TFIIIC Antibodies »

Product Summary for TFIIIC Antibody

Immunogen

The immunogen recognized by this antibody maps to a region between residue 1475 and 1525 of human general transcription factor IIIC, polypeptide 1 (general transcription factor IIIC, 220kDa subunit) using the numbering given in entry NP_001511.2 (GeneID 2

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for TFIIIC Antibody

Immunohistochemistry: TFIIIC Antibody [NB100-60656]

Immunohistochemistry: TFIIIC Antibody [NB100-60656]

Immunohistochemistry: TFIIIC Antibody [NB100-60656] - Sample: FFPE section of human prostate carcinoma. Antibody: Affinity purified rabbit anti-GTF3C1/TFIIIC220 used at a dilution of 1:1,000 (1ug/ml). Detection: DAB
Immunohistochemistry-Paraffin: TFIIIC Antibody [NB100-60656]

Immunohistochemistry-Paraffin: TFIIIC Antibody [NB100-60656]

Immunohistochemistry-Paraffin: TFIIIC Antibody [NB100-60656] - FFPE section of human thyroid carcinoma. Affinity purified rabbit anti-TFIIIC used at a dilution of 1:250. Detection: DAB staining using Immunohistochemistry Accessory Kit
Immunohistochemistry-Paraffin: TFIIIC Antibody [NB100-60656]

Immunohistochemistry-Paraffin: TFIIIC Antibody [NB100-60656]

Immunohistochemistry-Paraffin: TFIIIC Antibody [NB100-60656] - FFPE section of human breast carcinoma. Affinity purified rabbit anti-TFIIIC used at a dilution of 1:250. Detection: DAB staining using Immunohistochemistry Accessory Kit
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Applications for TFIIIC Antibody

Application
Recommended Usage

Immunohistochemistry

1:500- 1:2000

Immunohistochemistry-Paraffin

1:100-1:500

Immunoprecipitation

2-5 ug/mg lysate
Application Notes
Epitope retrieval with citrate buffer pH6.0 is recommended for FFPE tissue sections.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris-Citrate/Phosphate (pH 7.0 - 8.0)

Preservative

0.09% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: TFIIIC

General transcription factor 3C polypeptide 1 (GTF3C1/TFIIIC220) is a subunit of the TFIIIC DNA-binding factor required for transcription of tRNA and 5S rRNA genes by RNA polymerase III. Human TFIIIC is composed of six subunits: TFIIIC220, TFIIIC110, TFIIIC102, TFIIIC90 and TFIIIC63, and TFIIIC35. The functional contribution of GTF3C1/TFIIIC220 to the TFIIIC complex has not been fully determined.

Alternate Names

general transcription factor 3C polypeptide 1, general transcription factor IIIC, polypeptide 1 (alpha subunit), general transcription factor IIIC, polypeptide 1 (alpha subunit, 220kD ), general transcription factor IIIC, polypeptide 1, alpha 220kDa, TF3C-alpha, TFIIIC, TFIIIC 220 kDa subunit, TFIIIC box B-binding subunit, TFIIIC220DKFZp686A111, TFIIICalpha, Transcription factor IIIC 220 kDa subunit, Transcription factor IIIC subunit alpha

Entrez Gene IDs

2975 (Human)

Gene Symbol

GTF3C1

UniProt

NP_001511.2 (Human)

Additional TFIIIC Products

Product Documents for TFIIIC Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for TFIIIC Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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