TFIIIC Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NB100-60657

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Validated:

Human, Mouse

Cited:

Human, Mouse

Applications

Validated:

Chromatin Immunoprecipitation (ChIP), Immunohistochemistry, Immunohistochemistry-Paraffin, Immunoprecipitation (Negative), Western Blot

Cited:

Chemotaxis, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

1.0 mg/ml

View all TFIIIC Antibodies »

Product Specifications

Immunogen

The immunogen recognized by this antibody maps to a region between residue 2059 and 2109 of human general transcription factor IIIC, polypeptide 1 (general transcription factor IIIC, 220kDa subunit) using the numbering given in entry NP_001511.2 (GeneID 2

Reactivity Notes

Mouse reactivity reported in scientific literature (PMID: 23966877).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for TFIIIC Antibody

Western Blot: TFIIIC Antibody [NB100-60657]

Western Blot: TFIIIC Antibody [NB100-60657]

Western Blot: TFIIIC Antibody [NB100-60657] - Detection of Human GTF3C1/TFIIIC220 on HeLa whole cell lysate using NB100-60657. GTF3C1/TFIIIC220 was efficiently IPed by rabbit anti-GTF3C1/TFIIIC220 antibodies NB100-60655 and NB100-60656.
Immunohistochemistry-Paraffin: TFIIIC Antibody [NB100-60657]

Immunohistochemistry-Paraffin: TFIIIC Antibody [NB100-60657]

Immunohistochemistry-Paraffin: TFIIIC Antibody [NB100-60657] - Human prostate carcinoma. Antibody used at a dilution of 1:1,000.

Applications for TFIIIC Antibody

Application
Recommended Usage

Immunohistochemistry

1:500 -1:2000

Immunohistochemistry-Paraffin

1:500 - 1:2000

Western Blot

1:2000-1:10000
Application Notes
Use in chromatin immunoprecipitation reported in scientific literature (PMID: 31759822).
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris-Citrate/Phosphate (pH 7.0 - 8.0)

Preservative

0.09% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: TFIIIC

General transcription factor 3C polypeptide 1 (GTF3C1/TFIIIC220) is a subunit of the TFIIIC DNA-binding factor required for transcription of tRNA and 5S rRNA genes by RNA polymerase III. Human TFIIIC is composed of six subunits: TFIIIC220, TFIIIC110, TFIIIC102, TFIIIC90 and TFIIIC63, and TFIIIC35. The functional contribution of GTF3C1/TFIIIC220 to the TFIIIC complex has not been fully determined.

Alternate Names

general transcription factor 3C polypeptide 1, general transcription factor IIIC, polypeptide 1 (alpha subunit), general transcription factor IIIC, polypeptide 1 (alpha subunit, 220kD ), general transcription factor IIIC, polypeptide 1, alpha 220kDa, TF3C-alpha, TFIIIC, TFIIIC 220 kDa subunit, TFIIIC box B-binding subunit, TFIIIC220DKFZp686A111, TFIIICalpha, Transcription factor IIIC 220 kDa subunit, Transcription factor IIIC subunit alpha

Entrez Gene IDs

2975 (Human)

Gene Symbol

GTF3C1

UniProt

NP_001511.2 (Human)

Additional TFIIIC Products

Product Documents for TFIIIC Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for TFIIIC Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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