TFIP11 Antibody (3H5)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-43044

Novus Biologicals, part of Bio-Techne
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NBP3-43044
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Key Product Details

Species Reactivity

Human

Applications

ELISA, Immunohistochemistry, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # 3H5

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all TFIP11 Antibodies »

Product Specifications

Immunogen

tuftelin interacting protein 11 - (Uniprot# Q9UBB9)

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Theoretical MW

97 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Applications for TFIP11 Antibody (3H5)

Application
Recommended Usage

Immunohistochemistry

1:50 - 1:500

Western Blot

1:200 - 1:1000

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

PBS (pH 7.3), 50% glycerol

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: TFIP11

Neurotensin (NT) initiates an intracellular response by interacting with the G protein-coupled receptors NTR1 (NTS1 receptor, high affinity NTR) and NTR2 (NTS2 receptor, levocabastine-sensitive neurotensin receptor), and the type I receptor NTR3 (NTS3 receptor, sortilin-1, Gp95). NT has a wide distribution in regions of the brain and in peripheral tissues where NT receptors can contribute to hypotension, hyperglycemia, hypothermia, antinociception and regulation of intestinal motility and secretion. HL-60 cells express NTR1, which can couple to Gq, Gi/o, or Gs. Alternative splicing of rat NTR2 can generate a 5-transmembrane domain variant isoform that is co-expressed with the full-length NTR2 throughout the brain and spinal cord. NTR3 activation in the murine microglial cell line N11 induces MIP-2, MCP-1, IL-1beta and TNFalpha in an ERK1/2 and Akt kinase-dependent manner.

Alternate Names

bK445C9.6, DKFZP434B194, FLJ22086, hNtr1, NTR1, Septin and tuftelin-interacting protein 1, STIP, STIP-1, TIP39Spp382, tuftelin interacting protein 11, tuftelin-interacting protein 11

Gene Symbol

TFIP11

Additional TFIP11 Products

Product Documents for TFIP11 Antibody (3H5)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for TFIP11 Antibody (3H5)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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