TfR (Transferrin R) Antibody (TFRC/1818) [DyLight 405]

Validated:

DyLight 405 (Excitation = 400 nm, Emission = 420 nm)

Monoclonal Mouse IgG2b Kappa Clone # TFRC/1818

Please see the vial label for concentration. If unlisted please contact technical services.

Recombinant extracellular fragment (around aa 94-212) of human TfR (Transferrin R) protein (exact sequence is proprietary) (Uniprot: P02786)

Cell surface

It recognizes a ~90-95kDa protein which is identified as cell surface transferrin receptor (CD71), a disulfide-bonded homodimeric glycoprotein of 180-190kDa. This monoclonal antibody is highly specific to CD71 and shows no cross-reaction with other related proteins. Ligand for transferrin receptor is the serum iron transport protein, transferrin. This receptor is broadly distributed in carcinomas, sarcomas, leukemias, and lymphomas. CD71/Transferrin receptor has been reported to be associated with cell proliferation in both normal and neoplastic tissues and useful in predicting clinical behavior or response to therapy in a number of malignancies including breast cancer.

Monoclonal

Mouse

IgG2b Kappa

This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Protein A or G purified

50mM Sodium Borate

0.05% Sodium Azide

Please see the vial label for concentration. If unlisted please contact technical services.

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Store at 4C in the dark.