TfR2 Antibody (5#)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-41109

Novus Biologicals, part of Bio-Techne
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NBP3-41109
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Key Product Details

Species Reactivity

Human

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG Clone # 5#

Concentration

1 mg/ml

View all TfR2 Antibodies »

Product Specifications

Immunogen

Immunized with recombinant Human TfR2 (Uniprot#: Q9UP52; Leu4-Leu87 (Uniprot#: Q9UP52)

Clonality

Monoclonal

Host

Mouse

Isotype

IgG

Applications for TfR2 Antibody (5#)

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

5-30ug/mL

Immunohistochemistry

5-30ug/mL

Western Blot

0.5-5ug/mL
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

0.01M PBS, pH7.4, 50% glycerol

Preservative

0.05% Proclin 300

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: TfR2

TFR2 is a gene that codes for a protein with three isoforms, with lengths of 801, 630, and 774 amino acids and weights of approximately 89, 70, and 86 kDa respectively. TFR2 helps in the cellular uptake of transferrin-bound iron as well as iron metabolism, erythrocyte differentiation, and hepatocyte function. Current studies are being done on several diseases and disorders related to this gene including porphyria cutanea tarda, iron overload, beta thalassemia, liver cirrhosis, hepatitis C, fatty liver disease, leukemia, lymphoma, liver disease, and cystic fibrosis. TRF2 has also been shown to have interactions with HFE, TF, UBC, and SOCS3 in pathways such as the AMPK enzyme complex and iron metabolism in the placenta pathways.

Long Name

Transferrin Receptor 2

Alternate Names

HFE3, TFRC2

Gene Symbol

TFR2

Additional TfR2 Products

Product Documents for TfR2 Antibody (5#)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for TfR2 Antibody (5#)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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