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Thimet Oligopeptidase/THOP1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-55258

Novus Biologicals, part of Bio-Techne
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NBP2-55258
NBP2-55258-25ul

Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Summary for Thimet Oligopeptidase/THOP1 Antibody

Immunogen

This antibody was developed against a recombinant protein corresponding to the following amino acid sequence: AACAGDMADAASPCSVVNDLRWDLSAQQIEERTRELIEQTKRVYDQVGTQEFEDVSYESTLKA

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Thimet Oligopeptidase/THOP1 Antibody

Immunohistochemistry-Paraffin: Thimet Oligopeptidase/THOP1 Antibody [NBP2-55258]

Immunohistochemistry-Paraffin: Thimet Oligopeptidase/THOP1 Antibody [NBP2-55258]

Immunohistochemistry-Paraffin: Thimet Oligopeptidase/THOP1 Antibody [NBP2-55258] - Staining of human hippocampus shows distinct positivity in astrocytes and neuropil.

Applications for Thimet Oligopeptidase/THOP1 Antibody

Application
Recommended Usage

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Thimet Oligopeptidase/THOP1

Thimet oligopeptidase, a widely distributed enzyme in most species, plays a role in the metabolism of short neuropeptides (under 20 a.a. residues long). Thimet Oligopeptidase has an influential role in cytoplasmic peptide degradation. Other functions of Thimet Oligopeptidase include the degradation of amyloid precursor protein and the production of amyloidogenic fragments.

Alternate Names

EP24.15

Gene Symbol

THOP1

Additional Thimet Oligopeptidase/THOP1 Products

Product Documents for Thimet Oligopeptidase/THOP1 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Thimet Oligopeptidase/THOP1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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