Thioredoxin-1 Antibody (214)

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-89460

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # 214

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Thioredoxin-1 Antibodies »

Product Summary for Thioredoxin-1 Antibody (214)

Immunogen

This antibody was obtained from a rabbit immunized with purified, recombinant Human Thioredoxin-1 (Uniprot#: P10599; Met1-Val105).

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Description

This antibody can be stored at 2C-8C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20C to -80C. Avoid repeated freeze-thaw cycles.

Scientific Data Images for Thioredoxin-1 Antibody (214)

Immunohistochemistry-Paraffin: Thioredoxin-1 Antibody (214) [NBP2-89460]

Immunohistochemistry-Paraffin: Thioredoxin-1 Antibody (214) [NBP2-89460]

Immunohistochemistry-Paraffin: Thioredoxin-1 Antibody (214) [NBP2-89460] - Staining of human TXN in human appendix with rabbit monoclonal antibody (1:200). Positive staining was localized to intestinal gland.
Immunohistochemistry-Paraffin: Thioredoxin-1 Antibody (214) [NBP2-89460]

Immunohistochemistry-Paraffin: Thioredoxin-1 Antibody (214) [NBP2-89460]

Immunohistochemistry-Paraffin: Thioredoxin-1 Antibody (214) [NBP2-89460] - Staining of human TXN in human colon with rabbit monoclonal antibody (1:200). Positive staining was localized to colonic gland.

Applications for Thioredoxin-1 Antibody (214)

Application
Recommended Usage

Immunohistochemistry-Paraffin

1:100-1:500
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

0.2 um filtered solution in PBS

Preservative

No Preservative

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Thioredoxin-1

Thioredoxins (Trxs) are a group of small ubiquitous proteins that are key regulators of cellular redox balance. The mammalian Trx family includes the secreted and cellular protein (Trx-1), the mitochondria-specific Trx-2, the Trx-like cytosolic protein p32TrxL, a truncated version of Trx-1 known as Trx80, and the thioredoxin-related protein, TRP-14. Trx-1 is secreted by lymphocytes, hepatocytes, fibroblasts, and several tumor cells. Trx-1 acts as a growth factor an, antioxidant, a cofactor that provides reducing equivalents, and a transcriptional regulator. Expression of Trx-1 is increased under various stress conditions such as hypoxia and viral and bacterial infections. It also serves as a biomarker for rheumatoid arthritis.

Alternate Names

Thioredoxin1, Trx1, TXN, TXN1

Gene Symbol

TXN

Additional Thioredoxin-1 Products

Product Documents for Thioredoxin-1 Antibody (214)

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Thioredoxin-1 Antibody (214)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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