Thioredoxin-1 Antibody (S07-4H5)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-19933

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-19933-100ul
NBP3-19933-50ul
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # S07-4H5

Concentration

0.3 mg/ml

View all Thioredoxin-1 Antibodies »

Product Summary for Thioredoxin-1 Antibody (S07-4H5)

Immunogen

A synthetic peptide of human Thioredoxin-1 (Uniprot # P10599)

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

12 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Thioredoxin-1 Antibody (S07-4H5)

Western Blot: Thioredoxin-1 Antibody (S07-4H5) [NBP3-19933]

Western Blot: Thioredoxin-1 Antibody (S07-4H5) [NBP3-19933]

Western Blot: Thioredoxin-1 Antibody (S07-4H5) [NBP3-19933] - Western blot detection of Thioredoxin-1 in Jurkat, Hela cell lysates using NBP3-19933 (1:1000 diluted). Predicted band size: 12kDa. Observed band size: 12kDa.
Immunohistochemistry-Paraffin: Thioredoxin-1 Antibody (S07-4H5) [NBP3-19933]

Immunohistochemistry-Paraffin: Thioredoxin-1 Antibody (S07-4H5) [NBP3-19933]

Immunohistochemistry-Paraffin: Thioredoxin-1 Antibody (S07-4H5) [NBP3-19933] - Immunohistochemistry of Thioredoxin-1 in paraffin-embedded Human tonsil using NBP3-19933 at dilution 1/100

Applications for Thioredoxin-1 Antibody (S07-4H5)

Application
Recommended Usage

Immunohistochemistry

1/50-1/200

Western Blot

1/2000-1/10000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% BSA

Preservative

0.01% Sodium Azide

Concentration

0.3 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Thioredoxin-1

Thioredoxins (Trxs) are a group of small ubiquitous proteins that are key regulators of cellular redox balance. The mammalian Trx family includes the secreted and cellular protein (Trx-1), the mitochondria-specific Trx-2, the Trx-like cytosolic protein p32TrxL, a truncated version of Trx-1 known as Trx80, and the thioredoxin-related protein, TRP-14. Trx-1 is secreted by lymphocytes, hepatocytes, fibroblasts, and several tumor cells. Trx-1 acts as a growth factor an, antioxidant, a cofactor that provides reducing equivalents, and a transcriptional regulator. Expression of Trx-1 is increased under various stress conditions such as hypoxia and viral and bacterial infections. It also serves as a biomarker for rheumatoid arthritis.

Alternate Names

Thioredoxin1, Trx1, TXN, TXN1

Gene Symbol

TXN

Additional Thioredoxin-1 Products

Product Documents for Thioredoxin-1 Antibody (S07-4H5)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Thioredoxin-1 Antibody (S07-4H5)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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