Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

CyTOF-ready, Intracellular Staining by Flow Cytometry, Western Blot

Label

DyLight 405 (Excitation = 400 nm, Emission = 420 nm)

Antibody Source

Recombinant Monoclonal Mouse IgG1 Clone # 489804

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Thioredoxin Reductase 1/TRXR1 Antibodies »

Product Specifications

Immunogen

E. coli-derived recombinant mouse Thioredoxin Reductase 1/TRXR1
Met1-Ile497
Accession # Q16881

Specificity

Detects mouse Thioredoxin Reductase 1/TRXR1 in direct ELISAs and human, mouse, and rat Thioredoxin Reductase 1/TRXR1 in Western blots.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Applications for Thioredoxin Reductase 1/TRXR1 Antibody (489804) [DyLight 405]

Application
Recommended Usage

CyTOF-ready

Optimal dilutions of this antibody should be experimentally determined.

Intracellular Staining by Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: Thioredoxin Reductase 1/TRXR1

thioredoxin reductase 1 is a pyridine nucleotide oxidoreductase which reduces thioredoxins as well as other substrates, and plays a role in selenium metabolism and protection against oxidative stress. It is thought to function as a homodimer which uses FAD as a cofactor. Each subunit contains a selenocysteine residue which is required for the catalytic activity. Alternative splicing results in several transcript variants encoding the same protein. Additional transcript variants have been described but their biological validity has not been determined.

Alternate Names

GRIM-12, KDRF, TR1, TRXR1, TRXRD1, TXNR, TXNRD1

Gene Symbol

TXNRD1

Additional Thioredoxin Reductase 1/TRXR1 Products

Product Documents for Thioredoxin Reductase 1/TRXR1 Antibody (489804) [DyLight 405]

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for Thioredoxin Reductase 1/TRXR1 Antibody (489804) [DyLight 405]

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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