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Thrombospondin-1 Antibody (PSH02-97)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-33012

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-33012

Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # PSH02-97

Concentration

1 mg/ml

Product Specifications

Immunogen

Synthetic peptide within human Thrombospondin-1 aa 500-1,170 / 1,170. (Uniprot: P07996)

Localization

Endoplasmic reticulum. Sarcoplasmic reticulum.

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

129 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Thrombospondin-1 Antibody (PSH02-97)

Thrombospondin-1 Antibody (PSH02-97)

Western Blot: Thrombospondin-1 Antibody (PSH02-97) [NBP3-33012]

Western Blot: Thrombospondin-1 Antibody (PSH02-97) [NBP3-33012] - Western blot analysis of Thrombospondin-1 on different lysates with Rabbit anti-Thrombospondin-1 antibody (NBP3-33012) at 1/2,000 dilution.

Lane 1: HUVEC cell lysate
Lane 2: Mouse spleen tissue lysate
Lane 3: Rat spleen tissue lysate

Lysates/proteins at 40 ug/Lane.

Predicted band size: 129 kDa
Observed band size: 140kDa,170kDa,180 kDa

Exposure time: 1 minutes 2 seconds;

4-20% SDS-PAGE gel.

Proteins were transferred to a PVDF membrane and blocked with 5% NFDM/TBST for 1 hour at room temperature. The primary antibody (NBP3-33012) at 1/2,000 dilution was used in 5% NFDM/TBST at 4C overnight. Goat Anti-Rabbit IgG - HRP Secondary Antibody at 1/50,000 dilution was used for 1 hour at room temperature.
Thrombospondin-1 Antibody (PSH02-97)

Immunohistochemistry: Thrombospondin-1 Antibody (PSH02-97) [NBP3-33012]

Immunohistochemistry: Thrombospondin-1 Antibody (PSH02-97) [NBP3-33012] - Immunofluorescence analysis of paraffin-embedded mouse spleen tissue labeling Thrombospondin-1 with Rabbit anti-Thrombospondin-1 antibody (NBP3-33012) at 1/500 dilution.

The section was pre-treated using heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0) for 20 minutes. The tissues were blocked in 10% negative goat serum for 1 hour at room temperature, washed with PBS, and then probed with the primary antibody (NBP3-33012, green) at 1/500 dilution overnight at 4 ℃, washed with PBS. Goat Anti-Rabbit IgG H&L (iFluor™ 488) was used as the secondary antibody at 1/1,000 dilution. Nuclei were counterstained with DAPI (blue).
Thrombospondin-1 Antibody (PSH02-97)

Immunohistochemistry: Thrombospondin-1 Antibody (PSH02-97) [NBP3-33012]

Immunohistochemistry: Thrombospondin-1 Antibody (PSH02-97) [NBP3-33012] - Immunohistochemical analysis of paraffin-embedded human bone marrow tissue with Rabbit anti-Thrombospondin-1 antibody (NBP3-33012) at 1/2,000 dilution.

The section was pre-treated using heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0) for 20 minutes. The tissues were blocked in 1% BSA for 20 minutes at room temperature, washed with ddH2O and PBS, and then probed with the primary antibody (NBP3-33012) at 1/2,000 dilution for 1 hour at room temperature. The detection was performed using an HRP conjugated compact polymer system. DAB was used as the chromogen. Tissues were counterstained with hematoxylin and mounted with DPX.

Applications for Thrombospondin-1 Antibody (PSH02-97)

Application
Recommended Usage

Flow Cytometry

1:1000

Immunocytochemistry/ Immunofluorescence

1:100

Immunohistochemistry-Paraffin

1:2000-1:8000

Western Blot

1:2000

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS (pH7.4), 0.05% BSA and 40% Glycerol

Preservative

0.05% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Thrombospondin-1

Thrombospondin is a protein from platelet a granules. It is secreted at sites of platelet activation and aggregation and is involved in the differentiation of leukocytes, fibroblasts, smooth muscle and endothelial cells.

Alternate Names

THBS1, Thrombospondin1, TSP-1

Gene Symbol

THBS1

Additional Thrombospondin-1 Products

Product Documents for Thrombospondin-1 Antibody (PSH02-97)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Thrombospondin-1 Antibody (PSH02-97)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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