Thromboxane A2 R/TBXA2R Antibody (SR1893)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-22509

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-22509-100ul
NBP3-22509-50ul
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Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # SR1893

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Thromboxane A2 R/TBXA2R Antibodies »

Product Specifications

Immunogen

A synthesized peptide derived from human Thromboxane A2 R/TBXA2R (Uniprot #: P21731)

Specificity

Detects endogenous levels of total Thromboxane A2 R/TBXA2R

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

50 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Thromboxane A2 R/TBXA2R Antibody (SR1893)

Western Blot: Thromboxane A2 R/TBXA2R Antibody (SR1893) [NBP3-22509] -

Western Blot: Thromboxane A2 R/TBXA2R Antibody (SR1893) [NBP3-22509] - Western blot analysis using NBP3-22509 in human platelet cell lysate.

Applications for Thromboxane A2 R/TBXA2R Antibody (SR1893)

Application
Recommended Usage

Western Blot

1:500-1:2000

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.4, 150mM NaCl, 50% glycerol.

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Thromboxane A2 R/TBXA2R

The thromboxane A2 receptor (TBXA2R) is a member of the Prostanoid Receptor subfamily. TBXA2R performs an essential role in hemostasis by interacting with thromboxane A2 to induce platelet aggregation. Thromboxane A2 has been implicated in myocardial infarct, stroke, and asthma. Additionally, thromboxane-prostanoid receptors have been implicated in the pathogenesis of cardiovascular diseases. Changes in TBXA2R function have also been linked to a hereditary bleeding disorder. The thromboxane A2 receptor is encoded by a single gene that is alternatively spliced at the carboxyl terminus, resulting in two variants, TP (343 residues) and TP (407 residues) that share the first 328 amino acids.

Long Name

Thromboxane A2 Receptor

Alternate Names

BDPLT13, Prostanoid TP Receptor, TBXA2R, Thromboxane A2R, TP, TXA2R2

Gene Symbol

TBXA2R

Additional Thromboxane A2 R/TBXA2R Products

Product Documents for Thromboxane A2 R/TBXA2R Antibody (SR1893)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for Thromboxane A2 R/TBXA2R Antibody (SR1893)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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