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Thromboxane A2 R/TBXA2R Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-41242

Novus Biologicals, part of Bio-Techne
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NBP3-41242

Key Product Details

Species Reactivity

Human, Rat

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit

Concentration

0.5 mg/ml

Product Specifications

Immunogen

Immunized with recombinant Human Thromboxane A2 R/TBXA2R (Uniprot#: P21731; Pro3-Ser324 (Uniprot#: P21731)

Clonality

Polyclonal

Host

Rabbit

Applications for Thromboxane A2 R/TBXA2R Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

5-20ug/mL

Immunohistochemistry

5-20ug/mL

Western Blot

0.01-2ug/mL

Formulation, Preparation, and Storage

Purification

Antigen and protein A Affinity-purified

Formulation

PBS, pH7.4, 50% glycerol

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Thromboxane A2 R/TBXA2R

The thromboxane A2 receptor (TBXA2R) is a member of the Prostanoid Receptor subfamily. TBXA2R performs an essential role in hemostasis by interacting with thromboxane A2 to induce platelet aggregation. Thromboxane A2 has been implicated in myocardial infarct, stroke, and asthma. Additionally, thromboxane-prostanoid receptors have been implicated in the pathogenesis of cardiovascular diseases. Changes in TBXA2R function have also been linked to a hereditary bleeding disorder. The thromboxane A2 receptor is encoded by a single gene that is alternatively spliced at the carboxyl terminus, resulting in two variants, TP (343 residues) and TP (407 residues) that share the first 328 amino acids.

Long Name

Thromboxane A2 Receptor

Alternate Names

BDPLT13, Prostanoid TP Receptor, TBXA2R, Thromboxane A2R, TP, TXA2R2

Gene Symbol

TBXA2R

Additional Thromboxane A2 R/TBXA2R Products

Product Documents for Thromboxane A2 R/TBXA2R Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Thromboxane A2 R/TBXA2R Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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