Thymidylate Synthase Antibody (rTYMS/1884) [Biotin]

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-08887B

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Product Datasheet / COA / SDS

Recombinant Monoclonal Antibody

View Available Conjugates View Available Formulations

Conjugate

Catalog #

Unconjugated

NBP3-07145

Alexa Fluor 350

NBP3-08887AF350

Alexa Fluor 405

NBP3-08887AF405

Alexa Fluor 488

NBP3-08887AF488

Alexa Fluor 532

NBP3-08887AF532

Alexa Fluor 594

NBP3-08887AF594

Alexa Fluor 647

NBP3-08887AF647

Alexa Fluor 700

NBP3-08887AF700

Alexa Fluor 750

NBP3-08887AF750

Allophycocyanin

NBP3-08887APC

CoraFluor 1

NBP3-08887CL1

DyLight 350

NBP3-08887UV

DyLight 405

NBP3-08887V

DyLight 488

NBP3-08887G

DyLight 550

NBP3-08887R

DyLight 594

NBP3-08887DL594

DyLight 650

NBP3-08887C

DyLight 680

NBP3-08887FR

DyLight 755

NBP3-08887IR

FITC

NBP3-08887F

HRP

NBP3-08887H

Janelia Fluor 525

NBP3-08887JF525

Janelia Fluor 549

NBP3-08887JF549

Janelia Fluor 585

NBP3-08887JF585

Janelia Fluor 635

NBP3-08887JF635

Janelia Fluor 646

NBP3-08887JF646

Janelia Fluor 669

NBP3-08887JF669

mFluor Violet 450 SE

NBP3-08887MFV450

mFluor Violet 500 SE

NBP3-08887MFV500

mFluor Violet 610 SE

NBP3-08887MFV610

PE

NBP3-08887PE

PerCP

NBP3-08887PCP

Forumulation

Catalog #

Azide and BSA Free

NBP3-08887

Product Specifications
Applications
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Species Reactivity

Human

Applications

ELISA, Flow Cytometry, Immunocytochemistry/ Immunofluorescence

Label

Biotin

Antibody Source

Monoclonal Mouse IgG₁ kappa Clone # rTYMS/1884

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Thymidylate Synthase Antibodies »

Product Specifications

Immunogen

Recombinant human thymidylate synthase protein fragment (around aa 60-174) (exact sequence is proprietary) (Uniprot: P04818)

Localization

Nuclear & Cytoplasmic

Marker

5-FU Resistance Marker

Clonality

Monoclonal

Host

Mouse

Isotype

IgG₁ kappa

Applications for Thymidylate Synthase Antibody (rTYMS/1884) [Biotin]

Application

Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

Immunocytochemistry/ Immunofluorescence

Optimal dilutions of this antibody should be experimentally determined.

Application Notes

Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

PBS

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: Thymidylate Synthase

Thymidylate synthase (TS) is an intracellular enzyme critical for de novo synthesis of DNA. In cancer, expression of TS is often elevated and becomes further elevated as a result of treatment with the most commonly used chemotherapeutic, 5-fluorouracil (5-FU). Resistance or lack of response to 5-FU is attributed to the elevation of TS activity. Overexpression of TS has been demonstrated in many types of tumors including breast, colon, gastric and melanoma and is usually predictive of shortened survival time.

Long Name

Thymidylate synthase

Alternate Names

EC 2.1.1.45, OK/SW-cl.29, TS, TSase, TYMS

Gene Symbol

TYMS

Additional Thymidylate Synthase Products

Product Documents for Thymidylate Synthase Antibody (rTYMS/1884) [Biotin]

Product Datasheets

Download Product Datasheets

COA

SDS

Product Specific Notices for Thymidylate Synthase Antibody (rTYMS/1884) [Biotin]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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