TIMP-1 Antibody (MM0034-4A16) - Azide and BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NB110-61000

Novus Biologicals, part of Bio-Techne
Catalog #
Availability
Size / Price
Qty
NB110-61000
NB110-61000-0.025mg
Print Quote
Bulk Order
100% Guarantee

Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2 Clone # MM0034-4A16

Format

Azide and BSA Free

Concentration

LYOPH mg/ml

View all TIMP-1 Antibodies »

Product Summary for TIMP-1 Antibody (MM0034-4A16) - Azide and BSA Free

Immunogen

Human recombinant TIMP-1

Specificity

No cross-reactivity to human TIMP-2 is noted.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2

Scientific Data Images for TIMP-1 Antibody (MM0034-4A16) - Azide and BSA Free

Immunohistochemistry-Paraffin: TIMP-1 Antibody (MM0034-4A16) - Azide and BSA Free [NB110-61000]

Immunohistochemistry-Paraffin: TIMP-1 Antibody (MM0034-4A16) - Azide and BSA Free [NB110-61000]

Immunohistochemistry-Paraffin: TIMP1 Antibody (MM0034-4A16) [NB110-61000] - Formalin fixed and paraffin embedded normal human placenta tissue is subjected to mouse anti human TIMP-1

Applications for TIMP-1 Antibody (MM0034-4A16) - Azide and BSA Free

Application
Recommended Usage

Immunohistochemistry

1:10-1:500

Immunohistochemistry-Paraffin

1:25-1:50

Western Blot

1:100-1:1000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein G purified

Reconstitution

Reconstitute with sterilized PBS to a final concentration of 0.2 mg/ml.

Formulation

Lyophilized from a 0.2 um filtered solution in PBS. 0.025 mg size is provided in liquid form, PBS

Format

Azide and BSA Free

Preservative

No Preservative

Concentration

LYOPH mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: TIMP-1

Tissue inhibitor of metalloproteinases 1 (TIMP1) and Tissue inhibitor of metalloproteinases 2 (TIMP 2) have similar properties, specifically in inhibiting enzymes of matrix metalloproteinase family, and are thought to be of great importance in the maintenance of connective tissue integrity. TIMP1 forms a complex of 1:1 stoichiometry with activated interstitial collagenases, activated stromelysin, active form of 72kDa Type IV collagenase (also known as MMP2 or gelatinase A), and latent and active forms 92kDa Type IV collagenase (also known as MMP0 or gelatinase B). TIMPs inhibit the proteolytic invasiveness of tumour cells and normal placental trophoblast cells. TIMP1 is produced in low (pg/ml) levels by most cell types. Treatment of cells with the phorbol ester TPA stimulates production of TIMP1 in some cell types, but the low protein levels produced often require concentration of cell culture media to visualize the bands by Western Blotting.

Long Name

Tissue Inhibitors of Metalloproteinases 1

Alternate Names

TIMP1

Entrez Gene IDs

7076 (Human)

Gene Symbol

TIMP1

Additional TIMP-1 Products

Product Documents for TIMP-1 Antibody (MM0034-4A16) - Azide and BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for TIMP-1 Antibody (MM0034-4A16) - Azide and BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Privacy and Cookie Policy
Site Map
© Copyright 2024 Bio-Techne. All Rights Reserved.