TIP120B Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-33858

Novus Biologicals, part of Bio-Techne
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NBP2-33858
NBP2-33858-25ul
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Key Product Details

Species Reactivity

Human

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all TIP120B Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: MPVLVSGIIFSLADRSSSSTIRMDALAFLQGLLGTEPAEAFHPHLPILLPPVMACVADSFYKIAAEALVVLQELVRALWPLHRPRMLDPEPYVGEMSAVTLARLRATDLDQEVKERAISCMGH

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (89%), Rat (89%)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for TIP120B Antibody

Immunocytochemistry/ Immunofluorescence: TIP120B Antibody [NBP2-33858]

Immunocytochemistry/ Immunofluorescence: TIP120B Antibody [NBP2-33858]

Immunocytochemistry/Immunofluorescence: TIP120B Antibody [NBP2-33858] - Immunofluorescent staining of human cell line U-251 MG shows localization to nuclear bodies. Antibody staining is shown in green.
Immunohistochemistry-Paraffin: TIP120B Antibody [NBP2-33858]

Immunohistochemistry-Paraffin: TIP120B Antibody [NBP2-33858]

Immunohistochemistry-Paraffin: TIP120B Antibody [NBP2-33858] - Staining of human kidney shows strong cytoplasmic and membranous positivity in cells in tubules.

Applications for TIP120B Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: TIP120B

CAND2 is also known as TIP120B, and TATA-binding protein-interacting protein 120B. While both CAND1 (TIP120A) and CAND2 (TIP120B) are TATA-binding proteins and form complexes with various nuclear proteins involved in the control of eukaryotic gene transcription, CAND2 (TIP120B) is expressed specifically in muscle and heart tissue. This is contrary to the ubiquitous expression of CAND1 (TIP120A). TIP120 homologs exist in various higher eukaryotes including D. melanogaster, C. elegans, and A. thaliana. TIP120B is 60% identical in amino acid sequence to TIP120A.

Alternate Names

cullin-associated and neddylation-dissociated 2 (putative), Cullin-associated and neddylation-dissociated protein 2, cullin-associated NEDD8-dissociated protein 2, epididymis tissue protein Li 169, KIAA0667TBP-interacting protein of 120 kDa B, p120 CAND2, TBP interacting protein, TBP-interacting protein 120B, TIP120BTp120b

Gene Symbol

CAND2

UniProt

O75155 (Human)

Additional TIP120B Products

Product Documents for TIP120B Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for TIP120B Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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