Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # OTI2E6

Concentration

1 mg/ml

View all TIPIN Antibodies »

Product Specifications

Immunogen

Full length human recombinant protein of human TIPIN (NP_060328) produced in E.coli.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Theoretical MW

34.3 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for TIPIN Antibody (OTI2E6)

Western Blot: TIPIN Antibody (OTI2E6) [NBP2-46133]

Western Blot: TIPIN Antibody (OTI2E6) [NBP2-46133]

Western Blot: TIPIN Antibody (2E6) [NBP2-46133] - Analysis of HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY TIPIN.
Immunohistochemistry: TIPIN Antibody (OTI2E6) [NBP2-46133]

Immunohistochemistry: TIPIN Antibody (OTI2E6) [NBP2-46133]

Immunohistochemistry: TIPIN Antibody (2E6) [NBP2-46133] - Analysis of Human pancreas tissue. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min)
Immunohistochemistry: TIPIN Antibody (OTI2E6) [NBP2-46133]

Immunohistochemistry: TIPIN Antibody (OTI2E6) [NBP2-46133]

Immunohistochemistry: TIPIN Antibody (2E6) [NBP2-46133] - Analysis of Adenocarcinoma of Human colon tissue. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min)

Applications for TIPIN Antibody (OTI2E6)

Application
Recommended Usage

Immunohistochemistry

1:150

Immunohistochemistry-Paraffin

1:150

Western Blot

1:2000

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.3), 1.0% BSA and 50% Glycerol

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: TIPIN

Timeless-interacting protein (TIPIN) was originally isolated as a protein that interacts with timeless, a factor that plays a role in circadian rhythm and cell cycle checkpoint regulation. The TIM-TIPIN complex has been shown to coordinate the intra-S-phase checkpoint in response to UV-induced DNA damage. TIPIN is required for cell cycle arrest in response to DNA damage. It also interacts with RPA (replication protein A) on DNA and is able to slow down DNA chain elongation in response to UV-damage.

Alternate Names

FLJ20516, TIMELESS interacting protein, TIMELESS-interacting protein

Gene Symbol

TIPIN

Additional TIPIN Products

Product Documents for TIPIN Antibody (OTI2E6)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for TIPIN Antibody (OTI2E6)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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