Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 kappa Clone # VEGI/1283

Concentration

0.2 mg/ml

View all TL1A/TNFSF15 Antibodies »

Product Specifications

Immunogen

Recombinant human TL1A/TNFSF15 fragment (Uniprot: O95150)

Localization

Secreted and Cell Surface

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1 kappa

Theoretical MW

22 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Description

200ug/ml of antibody purified from Bioreactor Concentrate by Protein A or G. Prepared in 10 mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0 mg/ml. (NBP2-54513)

Antibody with azide - store at 2 to 8C. Antibody without azide - store at -20 to -80C.

Scientific Data Images for TL1A/TNFSF15 Antibody (VEGI/1283)

Immunohistochemistry-Paraffin: TL1A/TNFSF15 Antibody (VEGI/1283) [NBP2-53388]

Immunohistochemistry-Paraffin: TL1A/TNFSF15 Antibody (VEGI/1283) [NBP2-53388]

Immunohistochemistry-Paraffin: TL1A/TNFSF15 Antibody (VEGI/1283) [NBP2-53388] - Formalin-fixed, paraffin-embedded human Parathyroid Mass stained with VEGI Monoclonal Antibody (VEGI /1283).
Immunohistochemistry-Paraffin: TL1A/TNFSF15 Antibody (VEGI/1283) [NBP2-53388]

Immunohistochemistry-Paraffin: TL1A/TNFSF15 Antibody (VEGI/1283) [NBP2-53388]

Immunohistochemistry-Paraffin: TL1A/TNFSF15 Antibody (VEGI/1283) [NBP2-53388] - Formalin-fixed, paraffin-embedded human Colon Carcinoma stained with VEGI Monoclonal Antibody (VEGI /1283).

Applications for TL1A/TNFSF15 Antibody (VEGI/1283)

Application
Recommended Usage

Immunohistochemistry-Paraffin

1-2 ug/ml
Application Notes
Immunohistochemistry (Formalin-fixed): 1-2ug/ml for 30 minutes at RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95C followed by cooling at RT for 20 minutes.
Optimal dilution for a specific application should be determined.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

10 mM PBS with 0.05% BSA

Preservative

0.05% Sodium Azide

Concentration

0.2 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C.

Background: TL1A/TNFSF15

VEGI is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is abundantly expressed in endothelial cells, but is not expressed in either B or T cells. The expression of this protein is inducible by TNF and IL-1 alpha. This cytokine is a ligand for receptor TNFRSF25 and decoy receptor TNFRSF21/DR6. It can activate NF-kappaB and MAP kinases, and acts as an autocrine factor to induce apoptosis in endothelial cells. This cytokine is also found to inhibit endothelial cell proliferation, and thus may function as an angiogenesis inhibitor. An additional isoform encoded by an alternatively spliced transcript variant has been reported but the sequence of this transcript has not been determined

Long Name

TNF-like 1

Alternate Names

TNFSF15, VEGI

Gene Symbol

TNFSF15

UniProt

O95150

Additional TL1A/TNFSF15 Products

Product Documents for TL1A/TNFSF15 Antibody (VEGI/1283)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for TL1A/TNFSF15 Antibody (VEGI/1283)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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