TLR13 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-24539

Novus Biologicals, part of Bio-Techne
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NBP2-24539
NBP2-24539SS
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Key Product Details

Species Reactivity

Validated:

Mouse, Rat

Cited:

Mouse

Applications

Validated:

Flow (Intracellular), Flow Cytometry, Peptide ELISA, Western Blot

Cited:

Flow Cytometry Control

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

1.0 mg/ml

View all TLR13 Antibodies »

Product Specifications

Immunogen

A portion of amino acid 800 to 850 of mouse TLR13 was used as immunogen for this antibody.

Reactivity Notes

The amino acid sequence used as immunogen for this p65 NLS antibody is widely conserved in many species and isoforms including human, mouse, rat, rhesus monkey, chimp, bovine and horse.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for TLR13 Antibody

Western Blot: TLR13 Antibody [NBP2-24539]

Western Blot: TLR13 Antibody [NBP2-24539]

Western Blot: TLR13 Antibody [NBP2-24539] - analysis of TLR13 in rat corpus (tissue is from male rat reproductive tract) lysate in the 1) absence and 2) presence of immunizing peptide using TLR13 antibody at 1 ug/ml. I goat anti-rabbit Ig HRP secondary antibody and PicoTect ECL substrate solution were used for this test.
Flow Cytometry: TLR13 Antibody [NBP2-24539]

Flow Cytometry: TLR13 Antibody [NBP2-24539]

Flow Cytometry: TLR13 Antibody [NBP2-24539] - Intracellular analysis of TLR13 in the TLR13 stable cell line this antibody using TLR13 antibody at 1 ug/10^6 cells (green represents vector control, red represents TLR13 antibody).

Applications for TLR13 Antibody

Application
Recommended Usage

Flow (Intracellular)

reported in scientific literature (PMID 24518205)

Flow Cytometry

1-3 ug/10^6 cells

Peptide ELISA

1:100-1:2000

Western Blot

1-3 ug/ml

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS

Preservative

0.05% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: TLR13

TLRs make up a family of pattern recognition receptors that play important roles in the innate immune response. Broad classes of pathogens (e.g. viruses, bacteria, and fungi) constitutively express a set of mutation-resistant molecules called pathogen-associated molecular patterns (PAMPs). These microbial molecular markers may be composed of proteins, carbohydrates, lipids, nucleic acids and/or combinations thereof. Individual TLRs recognize distinct pathogen-associated PAMPs, initiating signaling cascades that promote the immune response. Structurally, TLRs are type I transmembrane receptors that possess varying numbers of extracellular N-terminal leucine-rich repeat (LRR) motifs, followed by a cysteine-rich region, a TM domain, and an intracellular Toll/IL-1 R (TIR) motif. The TIR motif is common to the larger IL-1 R/TLR superfamily.

Long Name

Toll-like Receptor 13

Alternate Names

TLR-13

Gene Symbol

TLR13

UniProt

Q6R5N8 (Human)

Additional TLR13 Products

Product Documents for TLR13 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for TLR13 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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