TMC1 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-05608

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all TMC1 Antibodies »

Product Specifications

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 600-700 of human TMC1 (NP_619636.2). INILRLHTSMYFQCWAVMCCNVPEARVFKASRSNNFYLGMLLLILFLSTMPVLYMIVSLPPSFDCGPFSGKNRMFEVIGETLEHDFPSWMAKILRQLSNPG

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

87 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for TMC1 Antibody - BSA Free

Western Blot: TMC1 AntibodyBSA Free [NBP3-05608]

Western Blot: TMC1 AntibodyBSA Free [NBP3-05608]

Western Blot: TMC1 Antibody [NBP3-05608] - Western blot analysis of extracts of mouse eye, using TMC1 antibody (NBP3-05608) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST._Detection: ECL Enhanced Kit. Exposure time: 90s.
Immunohistochemistry-Paraffin: TMC1 Antibody - BSA Free [NBP3-05608]

Immunohistochemistry-Paraffin: TMC1 Antibody - BSA Free [NBP3-05608]

Immunohistochemistry-Paraffin: TMC1 Antibody [NBP3-05608] - Immunohistochemistry of paraffin-embedded human esophagus using TMC1 antibody (NBP3-05608) at dilution of 1:100 (40x lens).
Immunohistochemistry-Paraffin: TMC1 Antibody - BSA Free [NBP3-05608]

Immunohistochemistry-Paraffin: TMC1 Antibody - BSA Free [NBP3-05608]

Immunohistochemistry-Paraffin: TMC1 Antibody [NBP3-05608] - Immunohistochemistry of paraffin-embedded rat brain using TMC1 antibody (NBP3-05608) at dilution of 1:100 (40x lens).
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Applications for TMC1 Antibody - BSA Free

Application
Recommended Usage

Immunohistochemistry

1:50-1:200

Western Blot

1:500-1:2000

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS with 50% glycerol, pH7.3.

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: TMC1

The TMC1 gene codes a 760 amino acid long, 87 kDA transmembrane channel-like protein 1 that is critical for the function of cochlear hair cells. The specific role of this gene, however, is unknown. This gene is known to interact with genes PRKAA1, MAP1LC3B, GABARAPL2, and NSMAF. Defects in the TMC1 gene cause deafness autosomal dominant type 36 and type 7. Additionally, it has been linked to nonsyndromic deafness, hearing loss, sensorineural hearing loss, megacolon, and enlarged vestibular aqueducts.

Alternate Names

DFNA36, DFNB11, DFNB7, transmembrane channel-like 1, transmembrane channel-like protein 1, Transmembrane cochlear-expressed protein 1, transmembrane, cochlear expressed, 1

Gene Symbol

TMC1

Additional TMC1 Products

Product Documents for TMC1 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for TMC1 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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