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TMCO3 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-48709

Novus Biologicals, part of Bio-Techne
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NBP2-48709
NBP2-48709-25ul

Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (92%), Rat (93%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Summary for TMCO3 Antibody

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: SVFQAVYGLQRALQGDYKDVVNMKESSRQRLEALREAAIKEETEYMELLAAEKHQVEALKNMQHQNQSLSMLDE

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for TMCO3 Antibody

Western Blot: TMCO3 Antibody [NBP2-48709]

Western Blot: TMCO3 Antibody [NBP2-48709]

Western Blot: TMCO3 Antibody [NBP2-48709] - Analysis in human cell line RT-4 and human cell line U-251 MG.
Immunohistochemistry: TMCO3 Antibody [NBP2-48709]

Immunohistochemistry: TMCO3 Antibody [NBP2-48709]

Immunohistochemistry: TMCO3 Antibody [NBP2-48709] - Staining of human breast shows strong positivity in a subset of glandular cells.

Applications for TMCO3 Antibody

Application
Recommended Usage

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: TMCO3

TMCO3, also known as Transmembrane And Coiled-Coil Domains 3, has a 677 amino acid long isoform that is approximately 76kDa, and two shorter isoforms that are 545 and 414 amino acids in length, respectively. TMCO3 is a membrane protein and may act as a sodium-hydrogen antiporter. Current research on TMCO3 has been conducted in relation to several diseases and disorders including dystonia and tuberculosis. TMCO3 has also been shown to have interactions with EGFR, ELAVL1 and Ubiquitin.

Alternate Names

B230339H12Rik, C13orf11, chromosome 13 open reading frame 11, FLJ20623, Putative LAG1-interacting protein, transmembrane and coiled-coil domain-containing protein 3, transmembrane and coiled-coil domains 3

Gene Symbol

TMCO3

Additional TMCO3 Products

Product Documents for TMCO3 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for TMCO3 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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