TMEFF2/Tomoregulin-2 Antibody (SR1696)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-22256

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-22256-100ul
NBP3-22256-50ul
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # SR1696

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all TMEFF2/Tomoregulin-2 Antibodies »

Product Summary for TMEFF2/Tomoregulin-2 Antibody (SR1696)

Immunogen

A synthesized peptide derived from human TMEFF2/Tomoregulin-2 (Uniprot #: Q9UIK5)

Specificity

Detects endogenous levels of total TMEFF2/Tomoregulin-2

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

41 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for TMEFF2/Tomoregulin-2 Antibody (SR1696)

Western Blot: TMEFF2/Tomoregulin-2 Antibody (SR1696) [NBP3-22256] -

Western Blot: TMEFF2/Tomoregulin-2 Antibody (SR1696) [NBP3-22256] - Western blot analysis using NBP3-22256 in LnCaP cell lysate.

Applications for TMEFF2/Tomoregulin-2 Antibody (SR1696)

Application
Recommended Usage

Flow Cytometry

1:50

Immunocytochemistry/ Immunofluorescence

1:50-1:200

Immunohistochemistry

1:50-1:200

Western Blot

1:500-1:2000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.4, 150mM NaCl, 50% glycerol.

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: TMEFF2/Tomoregulin-2

TMEFF2(transmembrane protein with EGF-like and two follistatin-like domains 2), a gene encoding a plasma membrane protein with two follistatin-like domains and one epidermal growth factor-like domain, had limited normal tissue distribution and was highly overexpressed in prostate cancer. The shedded form up-regulates cancer cell proliferation, probably by promoting ERK1/2 phosphorylation. Down-regulated in tumor cell lines in response to a high level of methylation in the 5' region. Clone J4B6, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human TMEFF2 protein.

Long Name

Transmembrane Protein with EFG-like and two Follistatin-like Domains

Alternate Names

TENB2, Tomoregulin-2, Tomoregulin2

Gene Symbol

TMEFF2

Additional TMEFF2/Tomoregulin-2 Products

Product Documents for TMEFF2/Tomoregulin-2 Antibody (SR1696)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for TMEFF2/Tomoregulin-2 Antibody (SR1696)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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