TMEM18 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-35869

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human, Rat

Applications

ELISA, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all TMEM18 Antibodies »

Product Specifications

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 40-100 of human TMEM18 (NP_690047.2).

Sequence:
LLTCLSSRSYRLQIGHFLCLVILVYCAEYINEAAAMNWRLFSKYQYFDSRGMFISIVFSAP

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

16 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for TMEM18 Antibody

TMEM18 Antibody

Western Blot: TMEM18 Antibody [NBP3-35869] -

Western Blot: TMEM18 Antibody [NBP3-35869] - Western blot analysis of various lysates using TMEM18at 1:1000 dilution.
Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit.
Exposure time: 3min.

Applications for TMEM18 Antibody

Application
Recommended Usage

Western Blot

1:500 - 1:2000

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.3), 50% glycerol

Preservative

0.01% Thimerosal

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: TMEM18

TMEM18 is an obesity risk gene. It is a small protein of 140 residues and is predicted to be mostly alpha-helical with three transmembrane parts. TMEM18 forms homooligomers, independently of the DNA-binding domain. TMEM18 localizes to the nuclear membrane and binds to DNA in a sequence-specific manner. TMEM18 is a transcription repressor sequence-specific ssDNA and dsDNA binding protein with preference for GCT end CTG repeats. TMEM18 is a cell migration modulator which enhances the glioma-specific migration ability of neural stem cells (NSC) and neural precursor cells (NPC).

Long Name

Transmembrane Protein 18

Alternate Names

transmembrane protein 18

Gene Symbol

TMEM18

Additional TMEM18 Products

Product Documents for TMEM18 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for TMEM18 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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