TMEM34 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-77144

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all TMEM34 Antibodies »

Product Specifications

Immunogen

Antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of human TMEM184C. The immunogen is located within amino acids 340 - 390 of TMEM184C. Amino Acid Squence: VRGHPRKKLFPEDQD

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Bovine (87%)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for TMEM34 Antibody - BSA Free

Western Blot: TMEM34 AntibodyBSA Free [NBP1-77144]

Western Blot: TMEM34 AntibodyBSA Free [NBP1-77144]

Western Blot: TMEM34 Antibody [NBP1-77144] - Analysis of TMEM184C in mouse heart tissue lysate with TMEM184C antibody at 1 ug/mL.
Immunocytochemistry/ Immunofluorescence: TMEM34 Antibody - BSA Free [NBP1-77144]

Immunocytochemistry/ Immunofluorescence: TMEM34 Antibody - BSA Free [NBP1-77144]

Immunocytochemistry/Immunofluorescence: TMEM34 Antibody [NBP1-77144] - Immunofluorescence of TMEM184C in mouse heart tissue with TMEM184B antibody at 20 ug/mL.
Immunohistochemistry-Paraffin: TMEM34 Antibody - BSA Free [NBP1-77144]

Immunohistochemistry-Paraffin: TMEM34 Antibody - BSA Free [NBP1-77144]

Immunohistochemistry-Paraffin: TMEM34 Antibody [NBP1-77144] - Mouse heart tissue with TMEM184C antibody at 5 ug/mL.
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Applications for TMEM34 Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Immunocytochemistry/ Immunofluorescence

20 ug/ml

Immunohistochemistry

5 ug/ml

Immunohistochemistry-Paraffin

5 ug/ml

Western Blot

1 ug/ml

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: TMEM34

Anaplastic thyroid cancer is one of the most lethal forms of cancer, but the precise carcinogenic mechanism has not been identified. TMEM184C, also known as TMEM34, was identified in a cDNA microarray analysis as being down-regulated in anaplastic thyroid cancers compared to normal thyroid tissues. TMEM184C protein expression was also lower in cell lines derived from these types of cancers compared to that of normal thyroid tissues or cell lines based on other types of thyroid cancers. Furthermore, transfection of TMEM34 into KTA2 cells led to the inhibition of cell growth, suggesting that TMEM184C might act as a tumor suppressor in anaplastic thyroid cancers.

Alternate Names

TMEM34, transmembrane protein 184C, Transmembrane protein 34FLJ10846

Gene Symbol

TMEM184C

UniProt

NP_060711 (Human)

Additional TMEM34 Products

Product Documents for TMEM34 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for TMEM34 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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