The protein encoded by the TNF Receptor I gene is a member of the TNF-receptor superfamily. This protein is one of the major receptors for the tumor necrosis factor-alpha. This receptor can activate NF-kappaB, mediate apoptosis, and function as a regulator of inflammation. Antiapoptotic protein BCL2-associated athanogene 4 (BAG4/SODD) and adaptor proteins TRADD and TRAF2 have been shown to interact with this receptor, and thus play regulatory roles in the signal transduction mediated by the receptor. Germline mutations of the extracellular domains of this receptor were found to be associated with the autosomal dominant periodic fever syndrome. The impaired receptor clearance is thought to be a mechanism of the disease. (provided by RefSeq)

Long Name

Tumor Necrosis Factor Receptor I

Alternate Names

CD120a, TNFRI, TNFRSF1A

Gene Symbol

TNFRSF1A

Additional TNF RI/TNFRSF1A Products

Product Documents for TNF RI/TNFRSF1A Antibody (001) [DyLight 550]

Product Datasheets

Download Product Datasheets

COA

SDS

Download SDS

Product Specific Notices for TNF RI/TNFRSF1A Antibody (001) [DyLight 550]

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Citations
Reviews

TNF RI/TNFRSF1A Antibody (001) [DyLight 550]

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-89687R

Key Product Details

Species Reactivity

Applications

Label

Antibody Source

Concentration

View all TNF RI/TNFRSF1A Antibodies »

Product Specifications

Immunogen

Clonality

Host

Isotype

Applications for TNF RI/TNFRSF1A Antibody (001) [DyLight 550]

Immunocytochemistry/ Immunofluorescence

Formulation, Preparation, and Storage

Purification

Formulation

Preservative

Concentration

Shipping

Stability & Storage

Background: TNF RI/TNFRSF1A