TNIP2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-48949

Novus Biologicals, part of Bio-Techne
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NBP2-48949
NBP2-48949-25ul
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Key Product Details

Species Reactivity

Human

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all TNIP2 Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: MLEQQILAYKDDFMSERADRERAQSRIQELEEKVASLLHQVSWRQDSREPDAGRIHAGSKTAKYLAADALELMVPGGWRP

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for TNIP2 Antibody

Immunocytochemistry/ Immunofluorescence: TNIP2 Antibody [NBP2-48949]

Immunocytochemistry/ Immunofluorescence: TNIP2 Antibody [NBP2-48949]

Immunocytochemistry/Immunofluorescence: TNIP2 Antibody [NBP2-48949] - Immunofluorescent staining of human cell line PC-3 shows localization to nucleus & cytosol.
Immunohistochemistry-Paraffin: TNIP2 Antibody [NBP2-48949]

Immunohistochemistry-Paraffin: TNIP2 Antibody [NBP2-48949]

Immunohistochemistry-Paraffin: TNIP2 Antibody [NBP2-48949] - Staining of human kidney shows cytoplasmic positivity in renal tubules.

Applications for TNIP2 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: TNIP2

ABIN-2, TNFAIP3 interacting protein 2, binds to the COOH-terminal zinc finger domain of A20. NF-kB activation induced by TNF and interleukin-1 is inhibited by overexpression of ABIN-2. The latter also inhibits NF-kB activation induced by overexpression of receptor-interacting protein or TNF receptor-associated factor 2. A-20 binding Inhibitor of Nuclear Factor-kappaB (NF-kB)Activation (ABIN-2) binds to A-20. ABIN-2 interferes with NF-kB activation upstream of the IKK complex and might contribute to NF-kB inhibitory function of A-20.

Alternate Names

A20-binding inhibitor of NF-kappa-B activation 2, A20-binding inhibitor of NF-kappaB activation-2, ABIN-2, ABIN2KLIP, Fetal liver LKB1-interacting protein, FLIP1DKFZp434J1313, MGC4289, TNFAIP3 interacting protein 2, TNFAIP3-interacting protein 2

Gene Symbol

TNIP2

Additional TNIP2 Products

Product Documents for TNIP2 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for TNIP2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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