Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Predicted:

Chicken (94%). Backed by our 100% Guarantee.

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all Tollip Antibodies »

Product Specifications

Immunogen

Antibody was raised against a 16 amino acid synthetic peptide from near the carboxy terminus of human TOLLIP. The immunogen is located within the last 50 amino acids of TOLLIP. Amino Acid Squence: RSVLEAQRGNKDAAINS

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Bovine (88%)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Tollip Antibody - BSA Free

Western Blot: Tollip AntibodyBSA Free [NBP1-76681]

Western Blot: Tollip AntibodyBSA Free [NBP1-76681]

Western Blot: Tollip Antibody [NBP1-76681] - Rat brain cell lysate with TOLLIP antibody at (A) 1 and (B) 2 ug/ml.
Tollip Antibody - BSA Free

Immunocytochemistry/ Immunofluorescence: Tollip Antibody - BSA Free [NBP1-76681] -

Immunocytochemistry/ Immunofluorescence: Tollip Antibody - BSA Free [NBP1-76681] - Immunofluorescence of Tollip in human brain tissue with Tollip antibody at 20 ug/ml.

Green: Tollip Antibody
Blue: DAPI staining
Tollip Antibody - BSA Free

Immunohistochemistry: Tollip Antibody - BSA Free [NBP1-76681] -

Immunohistochemistry: Tollip Antibody - BSA Free [NBP1-76681] - Immunohistochemistry of Tollip in human brain tissue with Tollip antibody at 5 ug/ml.
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Applications for Tollip Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Immunocytochemistry/ Immunofluorescence

2-20 ug/ml

Immunohistochemistry

5 ug/ml

Immunohistochemistry-Paraffin

5 ug/ml

Western Blot

1-2 ug/ml

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Tollip

Toll-like receptors (TLRs) are evolutionarily conserved pattern-recognition molecules resembling the toll proteins that mediate antimicrobial responses in Drosophila. These proteins recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. The TLRs act through adaptor molecules to activate various kinases and transcription factors so the organism can respond to potential infection. These adaptor molecules include TOLLIP, MyD88, and TRIF. TOLLIP associates directly with TLR2 and TLR 4, acting as an inhibitor to TLR activation. This negative regulation of TLR signaling may serve to limit the production of proinflammatory mediators during infection and inflammation.

Long Name

Toll Interacting Protein

Alternate Names

IL-1RAcPIP

Gene Symbol

TOLLIP

UniProt

AAH18272 (Human)

Additional Tollip Products

Product Documents for Tollip Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for Tollip Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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