Tomosyn Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-56176

Novus Biologicals, part of Bio-Techne
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NBP2-56176
NBP2-56176-25ul
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Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Validated:

Human

Predicted:

Mouse (95%), Rat (93%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Tomosyn Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to the following amino acid sequence: SAHVIIYRFSKQEVITEVIPMLEVRLLYEINDVETPEGEQPPPLPTPVGGSNPQPIPPQSHPSTSSSSSDGLRDN

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Tomosyn Antibody

Immunocytochemistry/ Immunofluorescence: Tomosyn Antibody [NBP2-56176]

Immunocytochemistry/ Immunofluorescence: Tomosyn Antibody [NBP2-56176]

Immunocytochemistry/Immunofluorescence: Tomosyn Antibody [NBP2-56176] - Staining of human cell line U-2 OS shows localization to cytosol.
Immunohistochemistry-Paraffin: Tomosyn Antibody [NBP2-56176]

Immunohistochemistry-Paraffin: Tomosyn Antibody [NBP2-56176]

Immunohistochemistry-Paraffin: Tomosyn Antibody [NBP2-56176] - Staining in human parathyroid gland and liver tissues using anti-STXBP5 antibody. Corresponding STXBP5 RNA-seq data are presented for the same tissues.
Immunohistochemistry-Paraffin: Tomosyn Antibody [NBP2-56176]

Immunohistochemistry-Paraffin: Tomosyn Antibody [NBP2-56176]

Immunohistochemistry-Paraffin: Tomosyn Antibody [NBP2-56176] - Staining of human liver shows low expression as expected.
View 1 more images

Applications for Tomosyn Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:500 - 1:1000

Immunohistochemistry-Paraffin

1:500 - 1:1000
Application Notes
ICC/IF, Fixation Permeabilization: Use PFA/Triton X-100. IHC, Retrieval method: HIER pH6.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Tomosyn

Inhibits translocation of GLUT4 from intracellular vesicles to the plasma membrane. Plays a regulatory role in calcium-dependent exocytosis and neurotransmitter release. Inhibits membrane fusion between transport vesicles and the plasma membrane. May modulate the assembly of trans-SNARE complexes between transport vesicles and the plasma membrane. Competes with STXBP1 for STX1 binding.; SUBUNIT: Part of a complex that contains STXBP5, STX4A and SNAP23. Interacts with STX1A and STX4A via its v-SNARE homology domain. Part of a complex that contains STX1, STXBP5, SNAP25 and SYT1.

Alternate Names

FLJ30922, Lethal(2) giant larvae protein homolog 3, LGL3, LLGL3Nbla04300, MGC141942, MGC141968, putative protein product of Nbla04300, syntaxin binding protein 5 (tomosyn), syntaxin-binding protein 5, tomosyn, tomosyn-1

Gene Symbol

STXBP5

Additional Tomosyn Products

Product Documents for Tomosyn Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Tomosyn Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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