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TPD52L1/D53 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-06091

Novus Biologicals, part of Bio-Techne
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NBP1-06091

Key Product Details

Species Reactivity

Human

Applications

Peptide ELISA, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG

Concentration

0.5 mg/ml

Product Specifications

Immunogen

Peptide with sequence C-EPLQGTDEDAVASAD corresponding to internal region according to NP_003278.1, NP_001003395.1 , NP_001003396.1, NP_001003397.1.

Epitope

C-EPLQGTDEDAVASAD

Specificity

This antibody is expected to recognise isoforms 1, 3 and 4 (NP_003278.1, NP_001003396.1 and NP_001003397.1 resp.).

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for TPD52L1/D53 Antibody

Western Blot: TPD52L1/D53 Antibody [NBP1-06091]

Western Blot: TPD52L1/D53 Antibody [NBP1-06091]

Western Blot: TPD52L1/D53 Antibody [NBP1-06091] - Analysis of TPD52L1/D53 using this antibody at 0.1 ug/ml in Human Breast cancer lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Applications for TPD52L1/D53 Antibody

Application
Recommended Usage

Peptide ELISA

Detection limit 1:8000

Western Blot

0.1 - 0.3 ug/ml
Application Notes
WB: Approx. 26 kDa band observed in human breast cancer lysates (calculated MW of 22.5 kDa band according to NP_003278.1).

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: TPD52L1/D53

This gene encodes a member of the tumor protein D52 (TPD52) family. The encoded protein contains a coiled-coil domain and may form homo- or hetero-dimer with TPD52 family members. The protein is reported to be involved in cell proliferation and calcium signaling. It also interacts with the mitogen-activated protein kinase kinase kinase 5 (MAP3K5/ASK1) and positively regulates MAP3K5-induced apoptosis. Multiple alternatively spliced transcript variants have been observed, but the full-length nature of some variants has not yet been determined. [provided by RefSeq]

Alternate Names

D53, MGC8556, tumor protein D52-like 1hD53TPD52L2, tumor protein D52-like 2, tumor protein D53

Entrez Gene IDs

7164 (Human)

Gene Symbol

TPD52L1

Additional TPD52L1/D53 Products

Product Documents for TPD52L1/D53 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for TPD52L1/D53 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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