TRAF-2 Antibody (4A12D9) - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-61662

Novus Biologicals, part of Bio-Techne
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NBP2-61662
NBP2-61662-0.025ml
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Key Product Details

Species Reactivity

Human

Applications

ELISA, Flow Cytometry, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2B Clone # 4A12D9

Format

BSA Free

Concentration

1 mg/ml

View all TRAF-2 Antibodies »

Product Specifications

Immunogen

Purified recombinant fragment of human TRAF-2 (AA: 39-188) expressed in E. Coli.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2B

Theoretical MW

55.8 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for TRAF-2 Antibody (4A12D9) - BSA Free

Western Blot: TRAF-2 Antibody (4A12D9)BSA Free [NBP2-61662]

Western Blot: TRAF-2 Antibody (4A12D9)BSA Free [NBP2-61662]

Western Blot: TRAF-2 Antibody (4A12D9) [NBP2-61662] - Analysis using TRAF2 mAb against HEK293 (1) and TRAF2 (AA: 39-188)-hIgGFc transfected HEK293 (2) cell lysate.
Flow Cytometry: TRAF-2 Antibody (4A12D9) - BSA Free [NBP2-61662]

Flow Cytometry: TRAF-2 Antibody (4A12D9) - BSA Free [NBP2-61662]

Flow Cytometry: TRAF-2 Antibody (4A12D9) [NBP2-61662] - Analysis of Hela cells using TRAF2 mouse mAb (green) and negative control (red).
Western Blot: TRAF-2 Antibody (4A12D9)BSA Free [NBP2-61662]

Western Blot: TRAF-2 Antibody (4A12D9)BSA Free [NBP2-61662]

Western Blot: TRAF-2 Antibody (4A12D9) [NBP2-61662] - Analysis using TRAF2 mAb against human TRAF2 (AA: 39-188) recombinant protein. (Expected MW is 42.5 kDa)
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Applications for TRAF-2 Antibody (4A12D9) - BSA Free

Application
Recommended Usage

ELISA

1:10000

Flow Cytometry

1:200-1:400

Western Blot

1:500-1:2000

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS

Format

BSA Free

Preservative

0.05% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: TRAF-2

The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from members of the TNF receptor superfamily. This protein directly interacts with TNF receptors, and forms a heterodimeric complex with TRAF1. This protein is required for TNF-alpha-mediated activation of MAPK8/JNK and NF-kappaB. The protein complex formed by this protein and TRAF1 interacts with the inhibitor-of-apoptosis proteins (IAPs), and functions as a mediator of the anti-apoptotic signals from TNF receptors. The interaction of this protein with TRADD, a TNF receptor associated apoptotic signal transducer, ensures the recruitment of IAPs for the direct inhibition of caspase activation. BIRC2/c-IAP1, an apoptosis inhibitor possessing ubiquitin ligase activity, can unbiquitinate and induce the degradation of this protein, and thus potentiate TNF-induced apoptosis. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of only one transcript has been determined.;

Long Name

TNF Receptor-Associated Factor 2

Alternate Names

TRAF2, TRAP3

Gene Symbol

TRAF2

Additional TRAF-2 Products

Product Documents for TRAF-2 Antibody (4A12D9) - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for TRAF-2 Antibody (4A12D9) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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