TRAILR1/TNFRSF10A Antibody (101)

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-89476

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP2-89476-100ul
NBP2-89476-50ul
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Flow Cytometry

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # 101

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all TRAILR1/TNFRSF10A Antibodies »

Product Summary for TRAILR1/TNFRSF10A Antibody (101)

Immunogen

This antibody was obtained from a rabbit immunized with purified, recombinant Human TRAILR1/TNFRSF10A (Accession#: NP_003835.2; Met1-Asn239).

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Description

This antibody can be stored at 2C-8C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20C to -80C. Avoid repeated freeze-thaw cycles.

Scientific Data Images for TRAILR1/TNFRSF10A Antibody (101)

Flow Cytometry: TRAILR1/TNFRSF10A Antibody (101) [NBP2-89476]

Flow Cytometry: TRAILR1/TNFRSF10A Antibody (101) [NBP2-89476]

Flow Cytometry: TRAILR1/TNFRSF10A Antibody (101) [NBP2-89476] - Analysis of Human TNFRSF10A(CD261) on HeLa cells. Cells were stained with purified anti-Human TNFRSF10A(CD261) (Filled hisgram), then stained with a FITC-conjugated second step antibody. To demonstrate specificity of staining, the binding by was blocked by preincubation of the purified antibody with 20ug recombinant human TNFRSF10A(CD261) for 1 hour (Black solid line hisgram).

Applications for TRAILR1/TNFRSF10A Antibody (101)

Application
Recommended Usage

Flow Cytometry

1:25-1:100
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

0.2 um filtered solution in PBS

Preservative

No Preservative

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: TRAILR1/TNFRSF10A

TRAIL-R1 (CD261, DR4) is a type I transmembrane protein, also called TRAIL receptor 1. The ligand for this DR4 death receptor has been identified and termed TRAIL, which is a member of the TNF family. DR4, as many other receptors (Fas, TNFR1, etc.), mediates apoptosis and NF kappaB activation in many cells and tissues. Apoptosis, a programmed cell death, is a operating process in normal cellular differentiation and development of multicellular organisms. Apoptosis is induced by coupled of certain cytokines (TNF family - TNF, Fas ligand) and their death domain containing receptors (TNFR1, Fas receptor).

Long Name

TRAIL Receptor 1

Alternate Names

CD261, DR4, TNFRSF10A, TRAIL R1

Gene Symbol

TNFRSF10A

Additional TRAILR1/TNFRSF10A Products

Product Documents for TRAILR1/TNFRSF10A Antibody (101)

Product Datasheets

Certificate of Analysis

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Product Specific Notices for TRAILR1/TNFRSF10A Antibody (101)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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