TRAILR1/TNFRSF10A Antibody (TR1.02) - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-80069

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Validated:

Human

Applications

Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2B Clone # TR1.02

Format

BSA Free

Concentration

1 mg/ml

View all TRAILR1/TNFRSF10A Antibodies »

Product Summary for TRAILR1/TNFRSF10A Antibody (TR1.02) - BSA Free

Immunogen

Recombinant human TRAILR1/TNFRSF10A (DR4).

Specificity

Recognizes human TRAILR1/TNFRSF10A. Does not cross-react with human TRAIL-R2, -R3 or -R4.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2B

Scientific Data Images for TRAILR1/TNFRSF10A Antibody (TR1.02) - BSA Free

Immunohistochemistry-Paraffin: TRAILR1/TNFRSF10A Antibody (TR1.02) - BSA Free [NBP2-80069]

Immunohistochemistry-Paraffin: TRAILR1/TNFRSF10A Antibody (TR1.02) - BSA Free [NBP2-80069]

Immunohistochemistry-Paraffin: TRAILR1/TNFRSF10A Antibody (TR1.02) [NBP2-80069] - Negative control.
Immunohistochemistry-Paraffin: TRAILR1/TNFRSF10A Antibody (TR1.02) - BSA Free [NBP2-80069]

Immunohistochemistry-Paraffin: TRAILR1/TNFRSF10A Antibody (TR1.02) - BSA Free [NBP2-80069]

Immunohistochemistry-Paraffin: TRAILR1/TNFRSF10A Antibody (TR1.02) [NBP2-80069] - Immunohistochemistry detection of endogenous TRAIL-R1 in paraffin-embedded human carcinoma tissues (colon, tonsil) using mAb to TRAIL-R1 (TR1.02).

Applications for TRAILR1/TNFRSF10A Antibody (TR1.02) - BSA Free

Application
Recommended Usage

Immunohistochemistry-Paraffin

20 ug/mL
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS containing 10% glycerol

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: TRAILR1/TNFRSF10A

TRAIL-R1 (CD261, DR4) is a type I transmembrane protein, also called TRAIL receptor 1. The ligand for this DR4 death receptor has been identified and termed TRAIL, which is a member of the TNF family. DR4, as many other receptors (Fas, TNFR1, etc.), mediates apoptosis and NF kappaB activation in many cells and tissues. Apoptosis, a programmed cell death, is a operating process in normal cellular differentiation and development of multicellular organisms. Apoptosis is induced by coupled of certain cytokines (TNF family - TNF, Fas ligand) and their death domain containing receptors (TNFR1, Fas receptor).

Long Name

TRAIL Receptor 1

Alternate Names

CD261, DR4, TNFRSF10A, TRAIL R1

Gene Symbol

TNFRSF10A

Additional TRAILR1/TNFRSF10A Products

Product Documents for TRAILR1/TNFRSF10A Antibody (TR1.02) - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for TRAILR1/TNFRSF10A Antibody (TR1.02) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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