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TRAILR3/TNFRSF10C Antibody (SR1429)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-22617

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
Catalog #
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NBP3-22617-100ul
NBP3-22617-50ul

Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Applications

Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # SR1429

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Product Summary for TRAILR3/TNFRSF10C Antibody (SR1429)

Immunogen

A synthesized peptide derived from human TRAILR3/TNFRSF10C (Uniprot #: O14798)

Specificity

Detects endogenous levels of total TRAILR3/TNFRSF10C

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for TRAILR3/TNFRSF10C Antibody (SR1429)

Western Blot: TRAILR3/TNFRSF10C Antibody (SR1429) [NBP3-22617] -

Western Blot: TRAILR3/TNFRSF10C Antibody (SR1429) [NBP3-22617] - Western blot analysis using NBP3-22617 in Jurkat cell lysate.

Applications for TRAILR3/TNFRSF10C Antibody (SR1429)

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:50-1:200

Western Blot

1:500-1:2000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.4, 150mM NaCl, 50% glycerol.

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: TRAIL R3/TNFRSF10C

DcR1 / TRAIL-R3 / TRID / LIT is one of the two putative decoy receptors identified for TRAIL, one of the members of TNF family of apoptosis inducing proteins. The other putative decoy receptor is called DcR2 / TRUNDD / TRAIL-R4. DcR1 is attached to the cell surface through glycophospholipid anchor. It has the extracellular TRAIL binding domain but lacks the cytoplasmic domain to induce apoptotic signal. Hence overexpression of DcR1 inhibits the TRAIL induced apoptosis.

Long Name

TRAIL Receptor 3

Alternate Names

CD263, DcR1, TNFRSF10C, TRAILR3

Gene Symbol

TNFRSF10C

Additional TRAIL R3/TNFRSF10C Products

Product Documents for TRAILR3/TNFRSF10C Antibody (SR1429)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for TRAILR3/TNFRSF10C Antibody (SR1429)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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