TRAIP Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-87125

Novus Biologicals, part of Bio-Techne
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NBP1-87125
NBP1-87125-25ul
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Key Product Details

Validated by

Independent Antibodies

Species Reactivity

Validated:

Human, Xenopus

Cited:

Frog - Xenopus (African Clawed Frog)

Applications

Validated:

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Cited:

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all TRAIP Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: QSQRPEVEEMIRDMGVGQSAVEQLAVYCVSLKKEYENLKEARKASGEVADKLRKDLFSSRSKLQTVYSELDQAKLELKSAQKDLQSADKEIMSLK

Reactivity Notes

Xenopus reactivity reported in scientific literature (PMID: 30979826). Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (85%), Rat (88%)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for TRAIP Antibody

Immunohistochemistry-Paraffin: TRAIP Antibody [NBP1-87125]

Immunohistochemistry-Paraffin: TRAIP Antibody [NBP1-87125]

Immunohistochemistry-Paraffin: TRAIP Antibody [NBP1-87125] - Staining of human cerebral cortex, kidney, liver and testis using Anti-TRAIP antibody NBP1-87125 (A) shows similar protein distribution across tissues to independent antibody NBP2-48655 (B).
Western Blot: TRAIP Antibody [NBP1-87125]

Western Blot: TRAIP Antibody [NBP1-87125]

Western Blot: TRAIP Antibody [NBP1-87125] - TRAIP activity is required for Mcm7 ubiquitylation in mitosis. The same experiment from Fig 3B but with addition of the RNF213 blot. An asterisk "*" by the Psf2 blot indicates the band of cyclin A1delta that is recognized by the Psf2 antibody. Image collected and cropped by CiteAb from the following publication (https://www.life-science-alliance.org/lookup/doi/10.26508/lsa.201900390), licensed under a CC-BY license.
Immunohistochemistry-Paraffin: TRAIP Antibody [NBP1-87125]

Immunohistochemistry-Paraffin: TRAIP Antibody [NBP1-87125]

Immunohistochemistry-Paraffin: TRAIP Antibody [NBP1-87125] - Staining of human liver using Anti-TRAIP antibody.
View 3 more images

Applications for TRAIP Antibody

Application
Recommended Usage

Immunohistochemistry

1:500 - 1:1000

Immunohistochemistry-Paraffin

1:500-1:1000

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. Use in Western blot reported in scientific literature (PMID: 30979826).
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: TRAIP

The TNF receptor-associated factor (TRAF) family is a group of cytoplasmic adapter proteins that link a wide variety of cell surface receptors including the TNF and IL-1 receptor (TRNFR and IL-1R) superfamily to diverse signaling cascades involved in differentiation, proliferation, activation and apoptosis. TRIP (TRAF-interacting protein) was identified in 1997 as a component of receptor-TRAF signaling complexes (Lee, 1997). TRIP (also known as TRAIP) has been shown to associate with TRNFR2 or CD30 signaling complexes through its interaction with TRAF proteins and inhibit TRAF2-mediated NF-kB activation (Lee, 1997; Regamey et al, 2003). The recruitment of different TRAFs and TRAF associated proteins like TRIP to receptor complexes can help regulate and provide specificity to the intracellular signals triggered by the cell surface receptors.

Alternate Names

RNF206TRIPRING finger protein 206, TRAF interacting protein, TRAF-interacting protein

Gene Symbol

TRAIP

Additional TRAIP Products

Product Documents for TRAIP Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for TRAIP Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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