TRAM/TICAM2 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-05623

Novus Biologicals, part of Bio-Techne
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NBP3-05623-100ul
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Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all TRAM/TICAM2 Antibodies »

Product Specifications

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-235 of human TRAM/TICAM2 (NP_067681.1). MGIGKSKINSCPLSLSWGKRHSVDTSPGYHESDSKKSEDLSLCNVAEHSNTTEGPTGKQEGAQSVEEMFEEEAEEEVFLKFVILHAEDDTDEALRVQNLLQDDFGIKPGIIFAEMPCGRQHLQNLDDAVNGSAWTILLLTENFLRDTWCNFQFYTSLMNSVNRQHKYNSVIPMRPLNNPLPRERTPFALQTINALEEESRGFPTQVERIFQESVYKTQQTIWKETRNMVQRQFIA

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for TRAM/TICAM2 Antibody - BSA Free

Western Blot: TRAM/TICAM2 AntibodyBSA Free [NBP3-05623]

Western Blot: TRAM/TICAM2 AntibodyBSA Free [NBP3-05623]

Western Blot: TRAM/TICAM2 Antibody [NBP3-05623] - Western blot analysis of extracts of various cell lines, using TRAM/TICAM2 antibody (NBP3-05623) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.

Applications for TRAM/TICAM2 Antibody - BSA Free

Application
Recommended Usage

Western Blot

1:500-1:2000

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS with 50% glycerol, pH7.3.

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: TRAM/TICAM2

TIRP is a member of the Toll/interleukin-1 receptor (TIR) family, a group of proteins that include the Toll-like receptors (TLRs) (1-3). TLRs are signaling molecules that recognize different pathogen-associated molecular patterns (PAMPs) and serve as an important link between the innate and adaptive immune responses (4). TIRP, along with other molecules such as TRIF, MAL, and MyD88, serves as an adaptor protein that allows for the interaction and activation of the IL-1R-associated kinase (IRAK) family, the subsequent activation of TNF receptor associated factor (TRAF)-6, and ultimately the activation of NF-kappaB (5). Expression of TIRP appears to be essential for TLR4 signalling (6).

Long Name

TRIF-related Adapter Molecule

Alternate Names

TICAM2, TIRAP3, TIRP, Trif

Gene Symbol

TICAM2

Additional TRAM/TICAM2 Products

Product Documents for TRAM/TICAM2 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

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Product Specific Notices for TRAM/TICAM2 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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