Transglutaminase 1/TGM1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-56535

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

0.5 mg/ml

View all Transglutaminase 1/TGM1 Antibodies »

Product Specifications

Immunogen

Synthetic peptides corresponding to TGM1(transglutaminase 1 (K polypeptide epidermal type I, protein-glutamine-gamma-glutamyltransferase)) The peptide sequence was selected from the N terminal of Transglutaminase 1 (NP_000350). Peptide sequence RGSSSGTRRPGSRGSDSRRPVSRGSGVNAAGDGTIREGMLVVNGVDLLSS The peptide sequence for this immunogen was taken from within the described region.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

90 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Description

The addition of 50% glycerol is optional for those storing this antibody at -20C and not aliquoting smaller units. However, please note that glycerol may interrupt some downstream antibody applications and should be added with caution.

Scientific Data Images for Transglutaminase 1/TGM1 Antibody

Western Blot: Transglutaminase 1/TGM1 Antibody [NBP1-56535]

Western Blot: Transglutaminase 1/TGM1 Antibody [NBP1-56535]

Western Blot: Transglutaminase 1/TGM1 Antibody [NBP1-56535] - Transfected 293T cell lysate, concentration 0.2-1 ug/ml.

Applications for Transglutaminase 1/TGM1 Antibody

Application
Recommended Usage

Western Blot

1.0 ug/ml

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, 2% Sucrose

Preservative

0.09% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Transglutaminase 1/TGM1

Transglutaminase 1 is a membrane protein that catalyzes the addition of an alkyl group from an akylamine to a glutamine residue of a protein, forming an alkylglutamine in the protein. This protein alkylation leads to crosslinking of proteins and catenation of polyamines to proteins. This gene contains either one or two copies of a 22 nt repeat unit in its 3' UTR. Mutations in this gene have been associated with autosomal recessive lamellar ichthyosis (LI) and nonbullous congenital ichthyosiform erythroderma (NCIE).The protein encoded by this gene is a membrane protein that catalyzes the addition of an alkyl group from an akylamine to a glutamine residue of a protein, forming an alkylglutamine in the protein. This protein alkylation leads to crosslinking of proteins and catenation of polyamines to proteins. This gene contains either one or two copies of a 22 nt repeat unit in its 3' UTR. Mutations in this gene have been associated with autosomal recessive lamellar ichthyosis (LI) and nonbullous congenital ichthyosiform erythroderma (NCIE). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Alternate Names

ICR2, KTG, LI1, TGase-1, TGK, TGM1

Entrez Gene IDs

7051 (Human)

Gene Symbol

TGM1

UniProt

P22735 (Human)

Additional Transglutaminase 1/TGM1 Products

Product Documents for Transglutaminase 1/TGM1 Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Transglutaminase 1/TGM1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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