Transglutaminase 2/TGM2 Antibody (CUB7402)

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-26458

Novus Biologicals, part of Bio-Techne
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NBP2-26458
NBP2-26458-0.05ml
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Key Product Details

Species Reactivity

Validated:

Human, Guinea Pig

Cited:

Mouse, Rat

Applications

Validated:

Immunohistochemistry, Immunohistochemistry-Paraffin

Cited:

Immunoprecipitation

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # CUB7402

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Transglutaminase 2/TGM2 Antibodies »

Product Specifications

Immunogen

BALB/C mice were injected with purified guinea pig liver TGase II.

Localization

Cytoplasmic, cell membrane, extracellular matrix

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Scientific Data Images for Transglutaminase 2/TGM2 Antibody (CUB7402)

Immunohistochemistry-Paraffin: Transglutaminase 2/TGM2 Antibody (CUB7402) [NBP2-26458]

Immunohistochemistry-Paraffin: Transglutaminase 2/TGM2 Antibody (CUB7402) [NBP2-26458]

Immunohistochemistry-Paraffin: Transglutaminase 2/TGM2 Antibody (CUB7402) [NBP2-26458] - Formalin fixed paraffin embedded breast carcinoma stained with Transglutaminase 2/TGM2 antibody (NBP2-26458).

Applications for Transglutaminase 2/TGM2 Antibody (CUB7402)

Application
Recommended Usage

Immunohistochemistry

1:50-1:75

Immunohistochemistry-Paraffin

1:50-1:75
Application Notes
IHC-P: recommended pretreatment of citrate buffer, pH 6.0. Recommended incubation time of 30 min at RT.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

PBS (pH 7.4), 0.2% BSA, Tween-20

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: Transglutaminase 2/TGM2

Principal Names: Transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase) Official Gene Symbol: TGM2 Gene ID: 7052 (Human) Gene Map Locus: 20q12 (Human). Tissue type transglutaminase (TGase II) is historically a member of the transglutaminase family that catalyzes a calcium-dependent acyl transfer reaction between peptide bound glutamine and a suitable primary amine. Transglutaminase has been implicated to play parts in diverse biologic processes such as cell proliferation, deposition and stabilization of the fine structure of the extracellular matrix and in wound repair and fibrosis. TGase II is an effector protein during cell death. The protein is induced by retinoic acid and is the autoantigen implicated in celiac disease. Transcript variants encoding three different isoforms have been found for this gene.

Alternate Names

TGC, TGM2, Transglutaminase 2, tTG

Gene Symbol

TGM2

Additional Transglutaminase 2/TGM2 Products

Product Documents for Transglutaminase 2/TGM2 Antibody (CUB7402)

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Transglutaminase 2/TGM2 Antibody (CUB7402)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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