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Transthyretin/Prealbumin Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-89649

Novus Biologicals, part of Bio-Techne
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NBP1-89649

Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human

Applications

Validated:

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Cited:

IF/IHC

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: GTGESKCPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYSTTAVVTNPKE

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (81%), Rat (83%).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Transthyretin/Prealbumin Antibody

Immunocytochemistry/ Immunofluorescence: Transthyretin/Prealbumin Antibody [NBP1-89649]

Immunocytochemistry/ Immunofluorescence: Transthyretin/Prealbumin Antibody [NBP1-89649]

Immunocytochemistry/Immunofluorescence: Transthyretin/Prealbumin Antibody [NBP1-89649] - Staining of human cell line CACO-2 shows localization to the Golgi apparatus. Antibody staining is shown in green.
Immunohistochemistry-Paraffin: Transthyretin/Prealbumin Antibody [NBP1-89649]

Immunohistochemistry-Paraffin: Transthyretin/Prealbumin Antibody [NBP1-89649]

Immunohistochemistry-Paraffin: Transthyretin/Prealbumin Antibody [NBP1-89649] - Staining of human liver shows moderate cytoplasmic positivity in hepatocytes.
Immunohistochemistry-Paraffin: Transthyretin/Prealbumin Antibody [NBP1-89649]

Immunohistochemistry-Paraffin: Transthyretin/Prealbumin Antibody [NBP1-89649]

Immunohistochemistry-Paraffin: Transthyretin/Prealbumin Antibody [NBP1-89649] - Staining of human skeletal muscle shows no cytoplasmic positivity in myocytes as expected.

Applications for Transthyretin/Prealbumin Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:1000 - 1:2500

Immunohistochemistry-Paraffin

1:1000 - 1:2500

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Transthyretin/Prealbumin

Prealbumin is a serum protein usually occurring at 200-400mg/L serum. Prealbumin migrates faster than albumin in acidic starch gels and include alpha 1 antitrypsin, thyroxine binding prealbumin, and orosomucoid, an alpha 1 acid glycoprotein. The functions of prealbumin are to transport thyroxine, a task it shares with thyroxine binding globulin, retinol binding protein and vitamin A. Polymorphism of prealbumin is known in the mouse and pig.

Alternate Names

ATTR, PALB, TBPA, TTR

Gene Symbol

TTR

Additional Transthyretin/Prealbumin Products

Product Documents for Transthyretin/Prealbumin Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Transthyretin/Prealbumin Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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