TREM1 Antibody (6B1) - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-21495

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Validated:

Human

Applications

ELISA, Flow Cytometry, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # 6B1

Format

BSA Free

Concentration

1 mg/ml

View all TREM-1 Antibodies »

Product Summary for TREM1 Antibody (6B1) - BSA Free

Immunogen

Recombinant human TREM1 fused with IgG

Epitope

The mouse monoclonal antibody 6B1 (also known as 6B1.1G12) recognizes an extracellular epitope of human TREM1.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Scientific Data Images for TREM1 Antibody (6B1) - BSA Free

Flow Cytometry: TREM1 Antibody (6B1) - BSA Free [NBP3-21495] -

Flow cytometry surface staining pattern of human peripheral whole blood stained using anti-human TREM1 (6B1) purified antibody (concentration in sample 1.67 ug/ml, GAM APC).

Flow Cytometry: TREM1 Antibody (6B1) - BSA Free [NBP3-21495] -

Separation of human neutrophil granulocytes (red-filled) from lymphocytes (black-dashed) in flow cytometry analysis (surface staining) of human peripheral whole blood stained using anti-human TREM1 (6B1) purified antibody (concentration in sample 1.67 ug/ml, GAM APC).

Applications for TREM1 Antibody (6B1) - BSA Free

Application
Recommended Usage

Flow Cytometry

1-4 ug/ml
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS, pH 7.4

Format

BSA Free

Preservative

0.9% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: TREM-1

Monocyte/macrophage- and neutrophil-mediated inflammatory responses can be stimulated through a variety of receptors, including G protein-linked 7-transmembrane receptors (e.g., FPR1; MIM 136537), Fc receptors (see MIM 146790), CD14 (MIM 158120) and Toll-like receptors (e.g., TLR4; MIM 603030), and cytokine receptors (e.g., IFNGR1; MIM 107470). Engagement of these receptors can also prime myeloid cells to respond to other stimuli. Myeloid cells express receptors belonging to the Ig superfamily, such as TREM1, or to the C-type lectin superfamily. Depending on their transmembrane and cytoplasmic sequence structure, these receptors have either activating (e.g., KIR2DS1; MIM 604952) or inhibitory functions (e.g., KIR2DL1; MIM 604936).[supplied by OMIM]

Long Name

Triggering Receptor Expressed on Myeloid Cells 1

Alternate Names

CD354, TREM1

Gene Symbol

TREM1

Additional TREM-1 Products

Product Documents for TREM1 Antibody (6B1) - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for TREM1 Antibody (6B1) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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