Monocyte/macrophage- and neutrophil-mediated inflammatory responses can be stimulated through a variety of receptors, including G protein-linked 7-transmembrane receptors (e.g., FPR1; MIM 136537), Fc receptors (see MIM 146790), CD14 (MIM 158120) and Toll-like receptors (e.g., TLR4; MIM 603030), and cytokine receptors (e.g., IFNGR1; MIM 107470). Engagement of these receptors can also prime myeloid cells to respond to other stimuli. Myeloid cells express receptors belonging to the Ig superfamily, such as TREM1, or to the C-type lectin superfamily. Depending on their transmembrane and cytoplasmic sequence structure, these receptors have either activating (e.g., KIR2DS1; MIM 604952) or inhibitory functions (e.g., KIR2DL1; MIM 604936).[supplied by OMIM]

Long Name

Triggering Receptor Expressed on Myeloid Cells 1

Alternate Names

CD354, TREM1

Gene Symbol

TREM1

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Product Specific Notices for TREM1 Antibody (PY159) [Janelia Fluor® 549]

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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TREM1 Antibody (PY159) [Janelia Fluor® 549]

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-28780JF549

Key Product Details

Species Reactivity

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Antibody Source

Concentration

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Product Specifications

Immunogen

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Isotype

Applications for TREM1 Antibody (PY159) [Janelia Fluor® 549]

ELISA

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Functional

Formulation, Preparation, and Storage

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Preservative

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Stability & Storage

Background: TREM-1