TREX1 Antibody (7Q0G6)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-16281

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-16281-100ul
NBP3-16281-20ul
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # 7Q0G6

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all TREX1 Antibodies »

Product Summary for TREX1 Antibody (7Q0G6)

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 150-314 of human TREX1 (Q9NSU2). AFCVDSITALKALERASSPSEHGPRKSYSLGSIYTRLYGQSPPDSHTAEGDVLALLSICQWRPQALLRWVDAHARPFGTIRPMYGVTASARTKPRPSAVTTTAHLATTRNTSPSLGESRGTKDLPPVKDPGALSREGLLAPLGLLAILTLAVATLYGLSLATPGE

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for TREX1 Antibody (7Q0G6)

Western Blot: TREX1 Antibody (7Q0G6) [NBP3-16281]

Western Blot: TREX1 Antibody (7Q0G6) [NBP3-16281]

Western Blot: TREX1 Antibody (7Q0G6) [NBP3-16281] - Western blot analysis of extracts of various cell lines, using TREX1 Rabbit mAb (NBP3-16281) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.

Applications for TREX1 Antibody (7Q0G6)

Application
Recommended Usage

Western Blot

1:500 - 1:2000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, 0.05% BSA, 50% glycerol, pH7.3

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: TREX1

TREX1 encodes the major 3'->5' DNA exonuclease in human cells. The protein is a non-processive exonuclease that may serve a proofreading function for a human DNA polymerase. It is also a component of the SET complex, and acts to rapidly degrade 3' ends of nicked DNA during granzyme A-mediated cell death. Mutations in this gene result in Aicardi-Goutieres syndrome, chilblain lupus, and Cree encephalitis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Alternate Names

3'-5' exonuclease TREX1, AGS1, Aicardi-Goutieres syndrome 1, CRV, DKFZp434J0310, DNase III, DRN3, EC 3.1.11.2, HERNS, three prime repair exonuclease 1,3' repair exonuclease 1

Gene Symbol

TREX1

Additional TREX1 Products

Product Documents for TREX1 Antibody (7Q0G6)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for TREX1 Antibody (7Q0G6)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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