TREX1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # H00011277-D01P

Novus Biologicals, part of Bio-Techne
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H00011277-D01P
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Key Product Details

Species Reactivity

Validated:

Human, Mouse

Cited:

Human

Applications

Immunocytochemistry/ Immunofluorescence, Immunoprecipitation, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all TREX1 Antibodies »

Product Specifications

Immunogen

TREX1 (NP_057465.1, 1 a.a. - 369 a.a.) full-length human protein. MGPGARRQGRIVQGRPEMCFCPPPTPLPPLRILTLGTHTPTPCSSPGSAAGTYPTMGSQALPPGPMQTLIFFDMEATGLPFSQPKVTELCLLAVHRCALESPPTSQGPPPTVPPPPRVVDKLSLCVAPGKACSPAASEITGLSTAVLAAHGRQCFDDNLANLLLAFLRRQPQPWCLVAHNGDRYDFPLLQAELAMLGLTSALDGAFCVDSITALKALERASSPSEHGPRKSYSLGSIYTRLYGQSPPDSHTAEGDVLALLSICQWRPQALLRWVDAHARPFGTIRPMYGVTASARTKPRPSAVTTTAHLATTRNTSPSLGESRGTKDLPPVKDPGALSREGLLAPLGLLAILTLAVATLYGLSLATPGE

Specificity

TREX1 - three prime repair exonuclease 1,

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for TREX1 Antibody

Western Blot: TREX1 Antibody [H00011277-D01P]

Western Blot: TREX1 Antibody [H00011277-D01P]

Western Blot: TREX1 Antibody [H00011277-D01P] - Analysis of TREX1 expression in K-562.
Western Blot: TREX1 Antibody [H00011277-D01P]

Western Blot: TREX1 Antibody [H00011277-D01P]

Western Blot: TREX1 Antibody [H00011277-D01P] - TREX1 MaxPab rabbit polyclonal antibody. Western Blot analysis of TREX1 expression in HepG2.
Western Blot: TREX1 Antibody [H00011277-D01P]

Western Blot: TREX1 Antibody [H00011277-D01P]

Western Blot: TREX1 Antibody [H00011277-D01P] - analysis of TREX1 expression in transfected 293T cell line by TREX1 MaxPab rabbit polyclonal antibody. Lane 1: TREX1 transfected lysate (38.90 KDa). Lane 2: Non-transfected lysate.
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Applications for TREX1 Antibody

Application
Recommended Usage

Western Blot

1:500
Application Notes
Antibody reactive against Recombinant Protein with GST tag on ELISA and Western Blot and also on transfected lysate in western blot. GST tag alone is used as a negative control.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS (pH 7.4)

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: TREX1

This gene encodes the major 3'->5' DNA exonuclease in human cells. The protein is a non-processive exonuclease that may serve a proofreading function for a human DNA polymerase. It is also a component of the SET complex, and acts to rapidly degrade 3' ends of nicked DNA during granzyme A-mediated cell death. Mutations in this gene result in Aicardi-Goutieres syndrome, chilblain lupus, and Cree encephalitis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Alternate Names

3'-5' exonuclease TREX1, AGS1, Aicardi-Goutieres syndrome 1, CRV, DKFZp434J0310, DNase III, DRN3, EC 3.1.11.2, HERNS, three prime repair exonuclease 1,3' repair exonuclease 1

Entrez Gene IDs

11277 (Human)

Gene Symbol

TREX1

UniProt

NP_057465.1 (Human)

Additional TREX1 Products

Product Documents for TREX1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for TREX1 Antibody

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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