Triadin Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-87417

Novus Biologicals, part of Bio-Techne
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NBP1-87417
NBP1-87417-25ul
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Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Validated:

Human

Cited:

Human

Applications

Validated:

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Cited:

Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Triadin Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: VSTRKESLQLHNVTKAEKPARVSKDVEDVPASKKAKEGTEDVSPTKQKSPISFFQCVYLDGYNGYGFQFP

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Triadin Antibody

Immunohistochemistry-Paraffin: Triadin Antibody [NBP1-87417]

Immunohistochemistry-Paraffin: Triadin Antibody [NBP1-87417]

Immunohistochemistry-Paraffin: Triadin Antibody [NBP1-87417] - Staining in human skeletal muscle and skin tissues using anti-TRDN antibody. Corresponding TRDN RNA-seq data are presented for the same tissues.
Immunocytochemistry/ Immunofluorescence: Triadin Antibody [NBP1-87417]

Immunocytochemistry/ Immunofluorescence: Triadin Antibody [NBP1-87417]

Immunocytochemistry/Immunofluorescence: Triadin Antibody [NBP1-87417] - Staining of human cell line A-431 shows localization to plasma membrane & cytosol. Antibody staining is shown in green.
Immunohistochemistry-Paraffin: Triadin Antibody [NBP1-87417]

Immunohistochemistry-Paraffin: Triadin Antibody [NBP1-87417]

Immunohistochemistry-Paraffin: Triadin Antibody [NBP1-87417] - Staining of human skeletal muscle shows high expression.
View 1 more images

Applications for Triadin Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Triadin

The junction between the transverse tubules (T-tubules) and the sarcoplasmic reticulum (SR) of skeletal muscle is called the triad. At the triad, dihydropyridine receptors (DHPR®s) of the T-tubule serve as voltage sensors in excitation-contraction coupling, while ryanodine receptors (RyR®s), the calcium release channels, exist in the membrane of the terminal cisternae of the SR. It is thought that during slow phase depolarization of the T-tubule, a third protein, Triadin (MW 95 kDa) transmits electrochemical signals to the SR through direct interaction with both DHPR®s and RyR®s. Though its exact role in this signaling process is unclear, triadin has been shown to co-localize with both DHPR and RYR at the junctional face of the terminal cisternae.

Alternate Names

dJ166D18.1 (triadin), TDN, triadin, TRISK

Gene Symbol

TRDN

Additional Triadin Products

Product Documents for Triadin Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Triadin Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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