TRIB3 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NB100-56398

Novus Biologicals, part of Bio-Techne
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NB100-56398
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Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human

Applications

Validated:

Immunocytochemistry/ Immunofluorescence, Western Blot

Cited:

Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

0.5 mg/ml

View all TRIB3 Antibodies »

Product Specifications

Immunogen

A synthetic peptide corresponding to amino acid residues 315-332 of human TRIB3. Genbank accession number: NM_021158.

Specificity

This detects a protein of approximate mol. wt. of 40 kDa in human liver lysate.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for TRIB3 Antibody

Western Blot: TRIB3 Antibody [NB100-56398]

Western Blot: TRIB3 Antibody [NB100-56398]

Western Blot: TRIB3 Antibody [NB100-56398] - Analysis of TRIB3 in human liver lysate.

Applications for TRIB3 Antibody

Application
Recommended Usage

Western Blot

1-3 ug/ml
Application Notes
)

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS containing 0.05% BSA

Preservative

0.05% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: TRIB3

A novel inhibitor of cell division, Tribbles, blocks mitosis at a critical point in Drosophila morphogenesis. Recently, mammalian homologues of Tribbles (Trbs) have been identified that control mitogen-activated protein kinase (MAPK) activity. TRIB3 also known as TRB-3, SINK, and SKIP3 is a member of Trbs family. Overexpression of this protein inhibits NF-kB-dependent transcription induced by tumor necrosis factor (TNF) stimulation or its downstream signaling proteins but does not inhibit NF-kB translocation to the nucleus and binding to DNA. TRIB3/SKIP3 is also overexpressed in multiple human tumors and is regulated by hypoxia.

Alternate Names

C20orf97, dJ1103G7.3, neuronal cell death inducible putative kinase, Neuronal cell death-inducible putative kinase, NIPK, p65-interacting inhibitor of NF-kappaB, p65-interacting inhibitor of NF-kappa-B, SINK, SKIP3, TRB-3, TRB3chromosome 20 open reading frame 97, tribbles homolog 3, tribbles homolog 3 (Drosophila)

Entrez Gene IDs

57761 (Human)

Gene Symbol

TRIB3

UniProt

Q96RU7 (Human)

Additional TRIB3 Products

Product Documents for TRIB3 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for TRIB3 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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