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TrkB [p Tyr707, p Tyr706] Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-54764

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Cited:

Rat

Applications

Validated:

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Cited:

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

Product Specifications

Immunogen

Trk B (phospho Tyr706/Tyr707) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 706/tyrosine 707 (T-D-Y (p)-Y (p)-R-V)derived from Human Trk B.

Modification

p Tyr706, p Tyr707

Specificity

The antibody detects endogenous levels of TrkB only when phosphorylated at tyrosine 706 and tyrosine 707.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

91 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for TrkB [p Tyr707, p Tyr706] Antibody - BSA Free

Immunohistochemistry-Paraffin: TrkB [p Tyr706] Antibody [NBP2-54764] - Human brain tissue using Trk B [P-Tyr706/Tyr707) antibody (left) or the same antibody preincubated with blocking peptide (right).

Applications for TrkB [p Tyr707, p Tyr706] Antibody - BSA Free

Application
Recommended Usage

Immunohistochemistry

1:10 - 1:200

Immunohistochemistry-Paraffin

1:10 - 1:500
Application Notes
This TrkB [p Tyr706] Antibody is validated for WB from a verified customer review.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Reviewed Applications

Read 1 review rated 3 using NBP2-54764 in the following applications:

Formulation, Preparation, and Storage

Purification

Epitope affinity purified

Formulation

PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20 degrees C. Avoid freeze/thaw cycles.

Background: TrkB

TrkB is a tyrosine-protein kinase receptor involved in the development and/or maintenance of the nervous system. TrkB is a receptor for brain-derived neurotrophic factor (BDNF), neurotrophin-3 and neurotrophin-4/5, but not nerve growth factor (NGF). The major substrates for the TRK receptors are SHC1, PI-3 kinase, and PLC-gamma-1.

Long Name

Neurotrophic Tyrosine Kinase Receptor B

Alternate Names

NTRK2

Gene Symbol

NTRK2

Additional TrkB Products

Product Documents for TrkB [p Tyr707, p Tyr706] Antibody - BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for TrkB [p Tyr707, p Tyr706] Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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