Troponin T type 1 (slow skeletal) Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-38855

Novus Biologicals, part of Bio-Techne
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NBP2-38855
NBP2-38855-25ul
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Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Validated:

Human

Predicted:

Mouse (97%), Rat (95%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Troponin T type 1 (slow skeletal) Antibodies »

Product Summary for Troponin T type 1 (slow skeletal) Antibody

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: EEEEAPEEPEPVAEPEEERPKPSRPVVPPLIPPKIPEGE

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Troponin T type 1 (slow skeletal) Antibody

Immunohistochemistry-Paraffin: Troponin T type 1 (slow skeletal) Antibody [NBP2-38855]

Immunohistochemistry-Paraffin: Troponin T type 1 (slow skeletal) Antibody [NBP2-38855]

Immunohistochemistry-Paraffin: Troponin T type 1 (slow skeletal) Antibody [NBP2-38855] - Staining in human skeletal muscle and lymph node tissues using anti-TNNT1 antibody. Corresponding TNNT1 RNA-seq data are presented for the same tissues.
Immunohistochemistry-Paraffin: Troponin T type 1 (slow skeletal) Antibody [NBP2-38855]

Immunohistochemistry-Paraffin: Troponin T type 1 (slow skeletal) Antibody [NBP2-38855]

Immunohistochemistry-Paraffin: Troponin T type 1 (slow skeletal) Antibody [NBP2-38855] - Staining of human kidney shows no positivity as expected.
Immunohistochemistry-Paraffin: Troponin T type 1 (slow skeletal) Antibody [NBP2-38855]

Immunohistochemistry-Paraffin: Troponin T type 1 (slow skeletal) Antibody [NBP2-38855]

Immunohistochemistry-Paraffin: Troponin T type 1 (slow skeletal) Antibody [NBP2-38855] - Staining of human skeletal muscle shows high expression.
View 2 more images

Applications for Troponin T type 1 (slow skeletal) Antibody

Application
Recommended Usage

Immunohistochemistry

1:500 - 1:1000

Immunohistochemistry-Paraffin

1:500 - 1:1000
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Troponin T type 1 (slow skeletal)

Troponin T type 1 encodes a protein that is a subunit of troponin, which is a regulatory complex located on the thin filament of the sarcomere. This complex regulates striated muscle contraction in response to fluctuations in intracellular calcium concentration. This complex is composed of three subunits: troponin C, which binds calcium, troponin T, which binds tropomyosin, and troponin I, which is an inhibitory subunit. This protein is the slow skeletal troponin T subunit. Mutations in this gene cause nemaline myopathy type 5, also known as Amish nemaline myopathy, a neuromuscular disorder characterized by muscle weakness and rod-shaped, or nemaline, inclusions in skeletal muscle fibers which affects infants, resulting in death due to respiratory insufficiency, usually in the second year. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Alternate Names

ANMtroponin T, slow skeletal muscle, FLJ98147, MGC104241, Slow skeletal muscle troponin T, sTnT, TNTS, TNTtroponin T1, skeletal, slow, troponin T type 1 (skeletal, slow), troponin-T1, skeletal, slow

Gene Symbol

TNNT1

UniProt

P13805 (Human)

Additional Troponin T type 1 (slow skeletal) Products

Product Documents for Troponin T type 1 (slow skeletal) Antibody

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Certificate of Analysis

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Product Specific Notices for Troponin T type 1 (slow skeletal) Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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