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Troponin T Type 2 (cardiac) Antibody (1A11)

Novus Biologicals, part of Bio-Techne | Catalog # NB120-10213

Novus Biologicals, part of Bio-Techne
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NB120-10213

Key Product Details

Species Reactivity

Validated:

Human, Rat (Negative)

Cited:

Human

Applications

Validated:

Immunoassay, Western Blot

Cited:

Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2B Clone # 1A11

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

Hybridoma clone has been derived from hybridization of Sp2/0 myeloma cells with spleen cells of Balb/c mice immunized with free human cTnT.

Epitope

a.a.r. 145-164

Reactivity Notes

Cross-reacts with Mouse, Cow, Cat, Dog, Fish, Goat, Pig, Rabbit and Human.Not yet tested in other species.

Specificity

No cross-reaction with skeletal TnT

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2B

Applications for Troponin T Type 2 (cardiac) Antibody (1A11)

Application
Recommended Usage

Immunoassay

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS (pH 7.4)

Preservative

0.09% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: Troponin T Type 2 (cardiac)

Cardiac Troponin T, a 36kDa protein, is the tropomyosin binding subunit of the troponin complex, which is located on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentration. Mutations within the protein have been associated with familial hypertrophic cardiomyopathy as well as with dilated cardiomyopathy. Transcripts for the gene undergo alternative splicing that results in many tissue specific isoforms.

Alternate Names

cardiac, CMD1D, CMPD2, dilated 1D (autosomal dominant), hypertrophic 2, MGC3889, RCM3, TnTc, troponin T type 2 (cardiac), troponin T, cardiac muscle

Entrez Gene IDs

7139 (Human)

Gene Symbol

TNNT2

UniProt

Additional Troponin T Type 2 (cardiac) Products

Product Documents for Troponin T Type 2 (cardiac) Antibody (1A11)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Troponin T Type 2 (cardiac) Antibody (1A11)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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