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TRPA1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-10359

Novus Biologicals, part of Bio-Techne
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NBP3-10359-100ul

Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit

Concentration

0.5 mg/ml

Product Summary for TRPA1 Antibody

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human TRPA1 (NP_015628). Peptide sequence KCTDRLDEDGNTALHFAAREGHAKAVALLLSHNADIVLNKQQASFLHLAL

Clonality

Polyclonal

Host

Rabbit

Theoretical MW

127 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for TRPA1 Antibody

Immunohistochemistry: TRPA1 Antibody [NBP3-10359]

Immunohistochemistry: TRPA1 Antibody [NBP3-10359]

Immunohistochemistry: TRPA1 Antibody [NBP3-10359] - Immunohistochemical analysis of rat sensory ganglia tissue

Applications for TRPA1 Antibody

Application
Recommended Usage

Western Blot

1.0 ug/ml
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, 2% Sucrose

Preservative

0.09% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: TRPA1

Transient receptor potential ion channels (TRPCs) are a superfamily of six transmembrane segment-spanning, gated cation channels. TRPA1 is a TRP-related channel that responds to cold temperatures and pungent compounds and plays a role in both nociceptor and hair cell transduction. It is a transformation-associated gene product in lung epithelia, whereas its protein distribution is primarily restricted to sensory neurons. Blocking TRPA1 may be a therapeutic target for treating cold hyperalgesia caused by inflammation and nerve damage. It is now known that TRPA1 protein is also widely expressed outside of the CNS and is dys-regulated during oncogenic transformation.

Long Name

Transient receptor potential cation channel subfamily A member 1

Alternate Names

ANKTM1, Wasabi receptor

Gene Symbol

TRPA1

Additional TRPA1 Products

Product Documents for TRPA1 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for TRPA1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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