TRPC1 Antibody (1E4)

Novus Biologicals, part of Bio-Techne | Catalog # H00007220-M03-50ug

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human

Applications

ELISA

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2b Kappa Clone # 1E4

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all TRPC1 Antibodies »

Product Specifications

Immunogen

TRPC1 (NP_003295, 442 a.a. ~ 505 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. AHNKFHDFADRKDWDAFHPTLVAEGLFAFANVLSYLRLFFMYTTSSILGPLQISMGQMLQDFGK

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2b Kappa

Scientific Data Images for TRPC1 Antibody (1E4)

ELISA: TRPC1 Antibody (1E4) [H00007220-M03-50ug]

ELISA: TRPC1 Antibody (1E4) [H00007220-M03-50ug]

ELISA: TRPC1 Antibody (1E4) [H00007220-M03-50ug] - Detection limit for recombinant GST tagged TRPC1 is 0.1 ng/ml as a capture antibody.
ELISA: TRPC1 Antibody (1E4) [H00007220-M03-50ug]

ELISA: TRPC1 Antibody (1E4) [H00007220-M03-50ug]

ELISA: TRPC1 Antibody (1E4) [H00007220-M03-50ug] - Detection limit for recombinant GST tagged TRPC1 is 0.3 ng/ml as a capture antibody.

Applications for TRPC1 Antibody (1E4)

Application
Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

In 1x PBS, pH 7.4

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: TRPC1

The TRP1 (TRPC1) gene encodes for a short transient receptor potential channel 1 protein which creates non-selective channels permeable to calcium and other cations. The long isoform is 793 amino acids long at around 91 kDA while the short isoform is 759 amino acids at approximately 87 kDA. These proteins are believed to be operated by a phosphatidylinositol messenger system. The TRP1 gene interacts with MX1, CAV1, ITPR3, HOMER1, and BMPR2 genes in pathways for CREB transcription, intracellular calcium signaling, developmental biology and pancreatic secretion. The TRP1 gene has been studied in various diseases such as kidney disease, breast cancer, neuroblastoma, prostatius, retinitis, basal cell carcinoma, muscular dystrophy, gingivitis, hypoxia, cerebritis, neurodegeneration, pyloric stenosis, and bipolar disorder.

Long Name

Short transient receptor potential channel 1

Alternate Names

TRP-1, TRP1

Entrez Gene IDs

7220 (Human)

Gene Symbol

TRPC1

OMIM

602343 (Human)

UniProt

NP_003295 (Human)

Additional TRPC1 Products

Product Documents for TRPC1 Antibody (1E4)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for TRPC1 Antibody (1E4)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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