TRPC6 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-77260

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all TRPC6 Antibodies »

Product Specifications

Immunogen

Antibody was raised against a 14 amino acid synthetic peptide from near the carboxy terminus of human TRPC6. The immunogen is located within the last 50 amino acids of TRPC6. Amino Acid Squence: LEEKSQNTEDLAEL

Specificity

This antibody may cross-react with TRPC3.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

93 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for TRPC6 Antibody - BSA Free

Western Blot: TRPC6 AntibodyBSA Free [NBP1-77260]

Western Blot: TRPC6 AntibodyBSA Free [NBP1-77260]

Western Blot: TRPC6 Antibody [NBP1-77260] - Mouse lung tissue lysate with TRPC6 antibody at (A) 0.5, (B) 1 and (C) 2 ug/ml.
Immunocytochemistry/ Immunofluorescence: TRPC6 Antibody - BSA Free [NBP1-77260]

Immunocytochemistry/ Immunofluorescence: TRPC6 Antibody - BSA Free [NBP1-77260]

Immunocytochemistry/Immunofluorescence: TRPC6 Antibody [NBP1-77260] - Immunofluorescence of TRPC6 in Mouse Lung cells with TRPC6 antibody at 20 ug/mL.
Immunohistochemistry-Paraffin: TRPC6 Antibody - BSA Free [NBP1-77260]

Immunohistochemistry-Paraffin: TRPC6 Antibody - BSA Free [NBP1-77260]

Immunohistochemistry-Paraffin: TRPC6 Antibody [NBP1-77260] - Staining of TRPC6 in mouse lung tissue with TRPC6 antibody at 5 ug/ml.
View 1 more images

Applications for TRPC6 Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Immunocytochemistry/ Immunofluorescence

20 ug/mL

Immunohistochemistry

10 ug/ml

Immunohistochemistry-Paraffin

10 ug/ml

Western Blot

0.5-2 ug/ml

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: TRPC6

The mammalian transient receptor potential (TRP) superfamily can be divided into three major families including the "canonical TRP" (TRPC) family. The seven members of this family share the activation through PLC-coupled receptors and have been suggested to be components of receptor-regulated cation channels in different cell types. Furthermore, the members of the TRPC6/6/7 subfamily can be activated by diacylglycerol (DAG) analogs, suggesting a possible mechanism of activation of these channels by PLC-coupled receptors. When expressed in transfected cells, TRPC6 acts as a non-selective store-independent receptor-activated cation channel. It is activated by DAG in a PKC-independent manner and is insensitive to IP3 activation. There is increasing evidence that TRPC6 encodes endogenous DAG-activated receptor-operated cation channels in vivo.

Long Name

Short transient receptor potential channel 6

Alternate Names

FSGS2, TRP-6, TRP6

Entrez Gene IDs

7225 (Human)

Gene Symbol

TRPC6

UniProt

Q9Y210 (Human)

Additional TRPC6 Products

Product Documents for TRPC6 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for TRPC6 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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